sulfite oxidase
Last updated 18 Aug 2020
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The SUOX gene provides instructions for making an enzyme called sulfite oxidase, which helps break down protein building blocks (amino acids) that contain sulfur when they are no longer needed. Specifically, sulfite oxidase is involved in the final step of this process, in which sulfur-containing molecules called sulfites are converted to other molecules called sulfates by adding an oxygen atom (a process called oxidation).
Normal function
The SUOX gene provides instructions for making an enzyme called sulfite oxidase, which helps break down protein building blocks (amino acids) that contain sulfur when they are no longer needed. Specifically, sulfite oxidase is involved in the final step of this process, in which sulfur-containing molecules called sulfites are converted to other molecules called sulfates by adding an oxygen atom (a process called oxidation).
Conditions referring to this gene or chromosome
Other names
sulfite oxidase, mitochondrial
Related patient information and medicines
Patient information leaflet
Can I take Methotrexate and Ibuprofen together?
If you notice your symptoms worsening,... Dairy products Milk and other dairy products contain an enzyme called xanthine oxidase which can break down methotrexate before it is absorbed. If you are taking methotrexate tablets, it is best to avoid consuming large amounts of dairy at the same time as your dose to ensure you get the full benefit of.
Patient information leaflet
Can I take Allopurinol and Mirtazapine together?
There are no known significant interactions between allopurinol and mirtazapine. It is generally considered safe to take these two medications together. Why this happens Allopurinol and mirtazapine are processed by different pathways in the body. Allopurinol works by blocking an enzyme called xanthine oxidase to lower uric acid levels, while.
Patient information leaflet
Can I take Methotrexate and Paracetamol together?
If you notice your symptoms worsening, you may need to limit your caffeine intake. Dairy products Milk and dairy products contain an enzyme called xanthine oxidase which can break down methotrexate in the digestive tract. To ensure you get the full dose, avoid consuming large amounts of dairy at the same time you take your methotrexate tablets..
Patient information leaflet
Decongestants
Decongestants are medicines that are used to help reduce the symptoms of a blocked or stuffy nose. They may be helpful for congestion caused by various conditions. Most commonly, decongestants are used for a cold, sinusitis, hay fever, allergies and rhinitis. These medicines are available as nose drops or nasal sprays and also as tablets, capsules.
Patient information leaflet
Persistent rhinitis
It usually causes no harm but some people are allergic to the tiny droppings (faeces) of the mite. House dust mites are present all year round but there is often a peak in their numbers in spring and autumn. Pets - flakes of dead animal skin as well as urine and saliva from pets, such as a cat, dog, horse, hamster, guinea pig, etc, are the cause.
Patient information leaflet
Cough medicines
Cough medicines are commonly bought to treat various types of coughs that occur when you have an upper respiratory tract infection (URTI). Cough medicines that you can buy are often divided into those for a dry or tickly cough, and those for a chesty cough. It is thought that cough medicines do not really work. However, some people feel that they.
Further reading and references
- sulfite oxidase; MedlinePlus, National Library of Medicine.
- Claerhout H, Witters P, Regal L, Jansen K, Van Hoestenberghe MR, Breckpot J, Vermeersch P. Isolated sulfite oxidase deficiency. J Inherit Metab Dis. 2018 Jan;41(1):101-108. doi: 10.1007/s10545-017-0089-4. Epub 2017 Oct 4.
- Karakas E, Kisker C. Structural analysis of missense mutations causing isolated sulfite oxidase deficiency. Dalton Trans. 2005 Nov 7;(21):3459-63. doi: 10.1039/b505789m. Epub 2005 Sep 26.
- Karakas E, Wilson HL, Graf TN, Xiang S, Jaramillo-Busquets S, Rajagopalan KV, Kisker C. Structural insights into sulfite oxidase deficiency. J Biol Chem. 2005 Sep 30;280(39):33506-15. doi: 10.1074/jbc.M505035200. Epub 2005 Jul 27.
- Sankaran BP, Nagappa M, Bharath RD, Taly AB. Isolated Sulfite Oxidase Deficiency. 2017 Sep 21. In: Adam MP, Bick S, Mirzaa GM, Wallace SE, Amemiya A, editors. GeneReviews(R) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2026. Available from http://www.ncbi.nlm.nih.gov/books/NBK453433/
- Tan WH, Eichler FS, Hoda S, Lee MS, Baris H, Hanley CA, Grant PE, Krishnamoorthy KS, Shih VE. Isolated sulfite oxidase deficiency: a case report with a novel mutation and review of the literature. Pediatrics. 2005 Sep;116(3):757-66. doi: 10.1542/peds.2004-1897.
- Zaki MS, Selim L, El-Bassyouni HT, Issa MY, Mahmoud I, Ismail S, Girgis M, Sadek AA, Gleeson JG, Abdel Hamid MS. Molybdenum cofactor and isolated sulphite oxidase deficiencies: Clinical and molecular spectrum among Egyptian patients. Eur J Paediatr Neurol. 2016 Sep;20(5):714-22. doi: 10.1016/j.ejpn.2016.05.011. Epub 2016 May 30.
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