Aripiprazole long-acting injection
Abilify Maintena
נבדק על ידי Sid Dajaniעודכן לאחרונה על ידי Michael Stewart, MRPharmSLast updated 20 Jul 2024
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Aripiprazole long-acting injection will be given to you by your doctor or nurse every month.
You may be asked to continue taking your tablets for 14 days after you have had your first injection.
If you miss an appointment for an injection, please make another appointment as soon as possible.
At a glance
Aripiprazole long-acting injection is an antipsychotic medicine for adults with schizophrenia.
It works by balancing chemical substances in the brain to help control symptoms like sensing things that are not real.
This injection is given once a month into the muscle, typically in the bottom or upper arm.
It is a long-acting form, meaning you do not have to remember to take tablets every day.
You may need to take tablets for 14 days after your first injection until it takes full effect.
Tell your doctor if you have other medical conditions or are taking other medicines before starting.
Contact your doctor immediately if you experience muscle stiffness, high temperature, confusion, fast heartbeat, and sweating.
במאמר זה:
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המשך לקרוא למטה
About aripiprazole long-acting injection
סוג התרופה | An antipsychotic medicine |
שימוש עבור | Schizophrenia in adults |
נקרא גם | Abilify Maintena® |
זמין כ | Long-acting intramuscular depot injection |
סכיזופרניה is a mental health condition that causes disordered ideas, beliefs and experiences. You will have been prescribed aripiprazole to relieve the symptoms of schizophrenia. Such symptoms include hearing, seeing, or sensing things that are not real, having mistaken beliefs, and feeling unusually suspicious. Aripiprazole works on the balance of chemical substances in your brain to help control these types of symptoms.
Long-acting, or 'depot', injections are used for maintenance once your symptoms have been eased by taking tablets. The injection slowly releases aripiprazole into your body. You will need to receive the injection regularly, once every month. The main advantage of a depot injection is that you do not have to remember to take tablets every day.
For information about taking aripiprazole tablets every day see our medicine leaflet called Aripiprazole (Abilify).
Before having aripiprazole long-acting injection
חזרה לתוכןSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start having aripiprazole it is important that your doctor knows:
אם את בהריון או מניקה.
If you have a heart condition or blood vessel disease.
If you have had a stroke, or if you have been told you have 'thickening' of the blood vessels to your brain.
If you have liver, kidney, or prostate problems.
If you have any problems with your breathing.
If you have any of the following: epilepsy, depression, Parkinson's disease, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called myasthenia gravis.
If you have ever had yellowing of your skin or the whites of your eyes (jaundice) or a blood disorder.
If you have a tumour on your adrenal gland (a condition called phaeochromocytoma).
If you have had an allergic reaction to a medicine.
אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.
המשך לקרוא למטה
How aripiprazole long-acting injection is given
חזרה לתוכןBefore you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. It will give you more information about aripiprazole and it will also provide you with a full list of the side-effects which you may experience from having it.
Aripiprazole injection will be given to you by a doctor or nurse. The injection is given into a muscle of your bottom (buttock) or your upper arm. You will be given an injection once every month - it is important that there is an interval of at least 26 days between each injection.
You may be asked to continue taking your tablets for 14 days after you have had your first injection. This is because it can take a few weeks before you feel the full effect from the injection.
להפיק את המרב מהטיפול שלך
חזרה לתוכןYour treatment will require careful monitoring to make sure that you get the best possible benefit from aripiprazole. Keep your regular doctor's appointments so that you get your injections on time, and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible.
If you are due to have any dental treatment or an operation, please tell the person carrying out the treatment that you have had an aripiprazole injection. This is important because it may interfere with any anaesthetic you receive.
If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with aripiprazole.
If you have diabetes you may need to check your blood glucose more frequently, as aripiprazole may affect the levels of sugar in your blood. Your doctor will advise you about this.
If you drink alcohol, please ask your doctor for advice. Alcohol increases the risk of side-effects from aripiprazole so it is best avoided.
Treatment with medicines like aripiprazole can sometimes cause problems with impulsive types of behaviour. If you notice any changes in your behaviour, such as an increased desire to gamble, you must let your doctor know as soon as possible.
A small number of people taking medicines like aripiprazole can have thoughts about harming themselves or ending their lives. It is very important that you tell your doctor about this if it happens to you.
המשך לקרוא למטה
Can aripiprazole long-acting injection cause problems?
חזרה לתוכןAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with aripiprazole long-acting injection. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Common aripiprazole long-acting injection side-effects (these affect fewer than 1 in 10 people) | מה אני יכול לעשות אם אני חווה את זה? |
תחושת סחרחורת, עייפות או נמנום | אל תנהג ואל תשתמש בכלים או במכונות. אל תשתה אלכוהול |
כאב ראש | שתו הרבה מים ובקשו מהרוקח שלכם להמליץ על משכך כאבים מתאים. אם הכאבי ראש נמשכים, הודיעו לרופא שלכם |
Feeling shaky or restless; unusual or uncontrollable movements | Speak with your doctor. You may be able to take another medicine to help reduce these effects |
Difficulties sleeping, feeling anxious, weight increase or weight loss, dry mouth, pain at the injection site, muscle stiffness, erectile dysfunction | Discuss these with your doctor if any become troublesome |
Changes to the results of some blood tests | הרופא שלך יבדוק את אלה |
חשוב: if you experience symptoms such as muscle stiffness, a very high temperature (fever) , feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.
Some side-effects of this medicine could affect your balance or make you feel unsteady and put you at risk of falling. Take extra care if you are frail, elderly or have any other risk factors for falls. Your doctor may also prescribe a lower dose of medication.
If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice.
מידע חשוב על כל התרופות
חזרה לתוכןמידע חשוב על כל התרופות
If you suspect that you have had an overdose of this medicine, go to the accident and emergency department of your local hospital at once.
אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.
דווח על תופעות לוואי לתרופה או חיסון
אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה Yellow Card website.

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בדוק אינטראקציות אפשריות בין תרופות, תוספים ומזונות לפני נטילתם יחד.
שאלות נפוצות
What is the purpose of switching from aripiprazole tablets to the long-acting injection?
The long-acting injection of aripiprazole, also known as a 'depot' injection, is used for ongoing maintenance of schizophrenia symptoms once they have been stabilised by the tablets. A key benefit is that it removes the need to remember to take tablets every day, as the injection slowly releases the medicine into your body over time.
How long will it take for the aripiprazole long-acting injection to start working after my first dose?
It can take a few weeks before you feel the full therapeutic effect from the injection. Because of this, you may be asked to continue taking your aripiprazole tablets for 14 days after receiving your first injection.
Are there any specific activities I should avoid while on aripiprazole long-acting injection?
Yes, if you feel dizzy, tired, or sleepy, you should not drive or operate machinery. It's also advisable to avoid alcohol, as it increases the risk of side-effects. Additionally, be aware that some side-effects might affect your balance or make you unsteady, so take extra care, especially if you are elderly or frail, to reduce the risk of falls.
How often will I need to get the aripiprazole long-acting injection?
You will need to receive the injection once every month. It is important to ensure there is at least an interval of 26 days between each injection.
What should I do if I miss an appointment for my aripiprazole injection?
If you miss an appointment for an injection, it's important to contact your doctor as soon as possible to arrange another appointment.
Can aripiprazole affect my blood sugar levels or weight?
Yes, aripiprazole can sometimes affect blood sugar levels, so if you have diabetes, you may need to check your blood glucose more frequently. Your doctor will provide advice on this. Weight increase or weight loss are also listed as possible side-effects. You should discuss any concerns about these with your doctor.
Where on the body is the aripiprazole long-acting injection usually given?
The injection is given into a muscle, specifically either in your bottom (buttock) or your upper arm.
קריאה נוספת והפניות
- Manufacturer's PIL, Abilify Maintena® 300 mg and 400 mg powder and solvent for prolonged-release suspension for injection; Otsuka Pharmaceuticals (UK) Ltd, The electronic Medicines Compendium. Dated April 204.
- תרופות מלאות BNF מהדורה 89; האגודה הרפואית הבריטית והחברה המלכותית לפרמקולוגיה של בריטניה הגדולה, לונדון.
המשך לקרוא למטה
About the authorView full bio

מייקל סטיוארט, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

סיד דג'אני
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
היסטוריית המאמר
המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.
Next review due: 24 Jul 2027
20 Jul 2024 | הגרסה האחרונה

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