Chloramphenicol for eye infections
Brolene, Golden Eye
נבדק על ידי Sid Dajaniעודכן לאחרונה על ידי Michael Stewart, MRPharmSLast updated 18 Jan 2024
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Use chloramphenicol eye drops every 2-4 hours to begin with, and then reduce the frequency to four times a day as your symptoms improve.
Use chloramphenicol eye ointment 3-4 times daily. Alternatively, if you are using chloramphenicol eye drops during the day, use the ointment once at bedtime.
If your vision becomes blurred for a short while after using chloramphenicol, do not drive and do not use tools until you can see clearly again.
Do not wear contact lenses during treatment and for 24 hours after your last dose.
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המשך לקרוא למטה
About chloramphenicol eye drops and ointment
סוג התרופה | An antibacterial eye preparation |
שימוש עבור | Eye infections |
נקרא גם | Brolene Antibiotic®; Clorogen®; Eykappo®; Golden Eye Antibiotic®; Minims® Chloramphenicol; Mollifye®; Optrex® Infected Eyes |
זמין כ | Eye drops, single-use eye drops, eye ointment |
Chloramphenicol eye drops and eye ointment are used to treat bacterial eye infections. Eye infections are a common cause of conjunctivitis. In conjunctivitis, your eye becomes inflamed, feels gritty, and may water more than usual. The white of your eye may look red, and your eyelids can become swollen and stuck together with a discharge when you wake up in the morning. Only one eye may be infected to begin with, but it often spreads to both eyes.
Most cases of infective conjunctivitis clear within a few days without treatment. For more severe infections, or for infections which do not clear on their own, an antibiotic eye drop or ointment such as chloramphenicol can be helpful.
Chloramphenicol works by helping to kill the bacteria which are causing the infection. It is available on prescription. You can also buy the drops and the ointment from a pharmacy, without a prescription, if it is for conjunctivitis in an adult or in a child over 2 years of age. Do not use chloramphenicol eye drops or ointment for a child under 2 years old, unless it has been prescribed by a doctor.
Before using chloramphenicol eye drops or eye ointment
חזרה לתוכןTo make sure this is the right treatment for you, before you start using chloramphenicol for an eye infection it is important that your doctor or pharmacist knows:
If you have a problem in your bone marrow or you or anyone in your family have a history of blood disorders.
If you have ever had an allergic reaction to chloramphenicol or to any other eye product.
אם את בהריון או מניקה.
If you wear soft contact lenses.
If you have raised pressure in your eye (glaucoma) or dry eye disease.
If you have had eye surgery or laser treatment within the previous six months.
If you suspect an eye injury or a foreign body in the eye.
If you are using any other eye drops or eye ointments.
המשך לקרוא למטה
How to use chloramphenicol eye drops
חזרה לתוכןWash your hands before you use the drops.
Remove the cap from the bottle (or the tip of the unit if you are using a single-use unit).
הטה את ראשך מעט לאחור ומשוך את העפעף התחתון של עינך כלפי מטה כדי ליצור כיס.
Hold the bottle (or single-use unit) upside down near to your eye. Try not to touch your eye as you do this.
Apply enough pressure to release one drop into your eye. Only use a second drop if the first drop missed going into your eye.
עצום את עינך לדקה או שתיים, ולחץ בעדינות על הצד של האף שלך שבו הפינה של העין שלך פוגשת את האף. זה עוזר למנוע מהטיפה להתנקז ושומר אותה בעין שלך.
Repeat the process in your other eye if both eyes are affected.
Replace the cap (or if you are using a single-use unit, throw the used unit away).
How to use chloramphenicol eye ointment
חזרה לתוכןWash your hands before you use the ointment.
Remove the cap from the tube.
הטה את ראשך מעט לאחור ומשוך את העפעף התחתון של עינך כלפי מטה כדי ליצור כיס.
Hold the tube upside down near to your eye.
Apply enough pressure to the tube to release a thin line of ointment along the inside of the lower eyelid. Try not to touch your eye as you do this.
Close your eye for a moment or two, and then blink a few times to spread the ointment around the inside of your eye.
Repeat the process in your other eye if both eyes are affected.
When you have finished, remember to replace the cap on the tube to prevent the ointment from becoming contaminated.
המשך לקרוא למטה
להפיק את המרב מהטיפול שלך
חזרה לתוכןBefore you start treating your eyes, read the manufacturer's printed information leaflet supplied with the product. It will give you more information about using chloramphenicol and will provide you with a full list of any side-effects which you may experience. If your eyes have an obvious discharge or 'crust', it can help if you bathe them with cool clean water before you use the chloramphenicol.
At first, chloramphenicol drops should be used every two to four hours unless you have been told otherwise. (Just use the drops while you are awake - you do not need to wake yourself up during the night to put them in.) As the infection improves, you can reduce the frequency down to four times a day. If you have been given chloramphenicol eye ointment to use as well as the eye drops, apply the ointment at night only. If you have been given chloramphenicol eye ointment without any drops, use the ointment three or four times each day.
Try not to miss any doses, but if you do forget, just use the drops/ointment as soon as you remember. Do not 'double up' the number of drops or the amount of ointment you use to make up for forgetting.
When you first put the eye drops or eye ointment into your eye, they can cause blurred vision. This should quickly clear. Make sure you can see clearly before you drive or use machines or tools.
Take care to avoid spreading the infection from one eye to the other, and to other members of your family. Washing your hands regularly (particularly after touching your eyes) and not sharing towels or pillows will help to prevent the infection from spreading.
If the tip of the tube/bottle touches your eye(s) when putting the drops in, it is a good idea to squeeze out two or three drops straightaway on to some tissue and rinse the tip with salt water.
Use chloramphenicol for a maximum of five days unless a doctor has told you otherwise. If your eyes are no better after two days of treatment, make an appointment to see your doctor for advice as soon as possible. You must also contact a doctor if your eyes become painful, if light hurts your eyes, or if your vision is impaired.
Eye infections can cause your eyes to become more sensitive to sunlight than usual. Wearing sunglasses can help ease this.
If you normally wear contact lenses, you should wear glasses until your symptoms have completely gone. It is recommended that you wait for 24 hours after you last use chloramphenicol before you put your lenses in again.
Can chloramphenicol eye preparations cause problems?
חזרה לתוכןChloramphenicol drops and ointment can occasionally cause mild eye irritation or stinging, but these usually soon pass and not everyone will experience them. If the irritation continues, or if you experience any other eye problems, please speak with your doctor or pharmacist for advice.
How to store chloramphenicol eye preparations
חזרה לתוכןשמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.
Chloramphenicol eye drops (including single-use units) must be kept in a fridge (2°C to 8°C).
Chloramphenicol eye ointment should be stored in a cool, dry place, away from direct heat and light.
Throw away the bottle or tube of chloramphenicol after you have finished the five-day course of treatment, even if there is some left. Never keep opened bottles or tubes to use later.
Single-use units should be used as soon as the unit is opened. Do not store or re-use opened units for subsequent doses. This is because the units do not contain any preservative.
מידע חשוב על כל התרופות
חזרה לתוכןמידע חשוב על כל התרופות
Make sure that the person supplying this medicine knows about any other medicines that you are taking or using. This includes any medicines you have bought, and herbal and homeopathic medicines.
אם אתה עובר ניתוח או טיפול שיניים, אמור לאדם שמבצע את הטיפול אילו תרופות אתה נוטל.
תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.
If you suspect that someone might have swallowed some of this medicine, contact your local accident and emergency department for advice.
אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.
אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.
MHRA - דיווח על תגובות שליליות
דווח על תופעות לוואי חשודות לתרופות, חיסונים, סיגריות אלקטרוניות, תקריות עם מכשירים רפואיים, מוצרים פגומים או מזויפים לסוכנות הרגולטורית לתרופות ומוצרי בריאות כדי להבטיח שימוש בטוח ויעיל.

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קריאה נוספת והפניות
- Manufacturer's PIL, Chloramphenicol 0.5% Eye Drops; FDC International Ltd, The electronic Medicines Compendium. Dated June 2021.
- תרופות מלאות BNF מהדורה 89; האגודה הרפואית הבריטית והחברה המלכותית לפרמקולוגיה של בריטניה הגדולה, לונדון.
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About the author

מייקל סטיוארט, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

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Next review due: 17 Jan 2027
18 Jan 2024 | הגרסה האחרונה

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