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Duloxetine for mood and nerve disorders

Cymbalta, Depalta, Duciltia

Duloxetine (Cymbalta®, Depalta® and Duciltia®) is prescribed to treat mood and nerve disorders. You may also be prescribed generic duloxetine capsules.

30 mg and 60 mg dosages are usually given for the treatment of depression, anxiety, and nerve pain.

Each time you collect a prescription from the pharmacy make sure the strength of your medicine (30 mg or 60 mg) is the same as before. Ask your pharmacist if you have any questions or concerns.

Common side effects of duloxetine include feeling sick (nausea), dry mouth, headache, constipation, and diarrhoea. Duloxetine can also make you feel dizzy or sleepy. If this happens, do not drive and do not use tools or machines.

Please tell your doctor if you feel that you are getting worse, or if you experience any troublesome side effects.

המשך לקרוא למטה

About duloxetine

סוג התרופה

A serotonin and noradrenaline reuptake inhibitor

שימוש עבור

Depression; anxiety disorder; pain caused by nerve damage in people with diabetes

נקרא גם

Cymbalta®; Depalta®; Duciltia®

זמין כ

קפסולות

Duloxetine is a type of antidepressant called a serotonin and noradrenaline reuptake inhibitor (SNRI). It is used to treat דיכאון, anxiety disorders, and pain caused by nerve damage in people with diabetes, called diabetic neuropathy.

Duloxetine is thought to work by regulating the levels of certain chemicals in your brain, called serotonin and noradrenaline/norepinephrine, helping to improve symptoms of depression, anxiety, and nerve pain.

Other uses

Duloxetine is also prescribed for treating urinary symptoms, although a different brand and strength of capsule are used. There is a separate medicine leaflet called Duloxetine for urinary symptoms, giving more information about duloxetine when used for this condition.

המשך לקרוא למטה

The most common side effects of duloxetine are:

  • תחושת בחילה.

  • יובש בפה.

  • עצירות.

  • שלשול.

  • Feeling dizzy, tired or sleepy.

  • כאב ראש.

  • Sweating.

  • Feeling anxious or shaky.

  • Trouble sleeping.

  • Reduced sex drive (libido).

You will find a full list in the manufacturer's information leaflet supplied with your medicine.

תופעות הלוואי הלא רצויות משתפרות לעיתים קרובות כאשר הגוף שלך מתרגל לתרופה החדשה, אך יש לפנות לרופא או לרוקח אם אחת מהתופעות הבאות נמשכת או הופכת למטרידה.

Very common duloxetine side effects (these affect more than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

Feeling sick

Eat simple meals - avoid rich or spicy foods

יובש בפה

נסה ללעוס מסטיק ללא סוכר או למצוץ סוכריות ללא סוכר

עצירות

Try to eat a well-balanced diet and drink several glasses of water each day

Common duloxetine side effects (these affect fewer than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

Blurred vision; feeling tired, dizzy or sleepy

Do not drive and do not use tools or machines while affected. Avoid alcohol

שלשול

שתו הרבה מים כדי להחליף נוזלים שאבדו

כאב ראש

שתו הרבה מים ובקשו מהרוקח שלכם להמליץ על משכך כאבים מתאים. אם הכאבי ראש נמשכים, הודיעו לרופא שלכם

Lack of appetite, indigestion, stomach pain, facial flushing, increased blood pressure, difficulty sleeping, feeling anxious, skin tingling, feeling shaky, reduced interest in sex, increased sweating

Discuss these with your doctor if any become troublesome

Important: if you develop any depressing or distressing thoughts or ideas, you should let your doctor know about this as soon as possible. When this medicine is prescribed for people with depression or anxiety, it can increase the risk of suicidal thoughts, particularly when the treatment is first started.

On rare occasions, medicines that affect the level of serotonin in the brain can cause it to go too high and cause problems. The risk is higher if you are taking another medicine with this effect (such as an antidepressant). Seek medical attention if you develop any combination of the following:

  • שרירים נוקשים או תנועות 'קופצניות'.

  • דופק מהיר באופן חריג.

  • High temperature (fever).

  • Feeling sick (nausea) or being sick (vomiting), diarrhoea.

  • תחושת בלבול או ראיית חזיונות (הזיות).

If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice

המשך לקרוא למטה

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking duloxetine it is important that your doctor knows:

  • אם את בהריון, מנסה להיכנס להריון או מניקה.

  • If you have problems with the way your liver works, or with the way your kidneys work.

  • If you have a heart condition.

  • If you have increased eye pressure (called glaucoma).

  • אם יש לך לחץ דם גבוה.

  • If you have ever had 'high' moods, such as mania in bipolar disorder.

  • If you have ever had a fit (seizure).

  • If you have a blood disorder that increases your risk of bleeding.

  • אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

  • Read the manufacturer's printed information leaflet from inside the pack. It will give you more information about duloxetine and will provide you with a full list of the side effects which you may experience from taking it.

  • Take duloxetine exactly as your doctor tells you to. The usual dose is one capsule of either 30 mg or 60 mg daily.

    • When starting duloxetine, your doctor may give you the lower strength of capsules to begin with, and then increase the strength as you go on.

  • Try to take your doses at the same time of day each day, as this will help you to remember to take your doses regularly.

    • You can take duloxetine either before or after meals. Swallow the capsule whole with a drink of water to help you to swallow it.

  • If you forget to take a dose at your usual time, take it when you remember. If you do not remember until the following day then leave out the forgotten dose and take your next dose when it is due. Do not take two doses together to make up for a missed dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress and review your treatment.

  • You may feel that duloxetine is not helping you straightaway. If you are taking duloxetine for depression or anxiety, it can take a week or two before the effect builds up and 2-4 weeks before you feel the full benefit.

  • If you are taking duloxetine for nerve pain damage, it can take several weeks before you feel better. Do not stop taking the capsules after a week or so, even if you think they are not working.

  • If you are taking duloxetine for depression, you should expect that a normal course of treatment will last for around six months after your symptoms have eased.

    • There are several types of antidepressants and they differ in their possible side effects - if you find that duloxetine does not suit you then let your doctor know, as another may be found that will.

  • If you drink alcohol, ask your doctor for advice about drinking while you are on duloxetine. Drinking alcohol can increase the risk of unwanted effects from duloxetine, such as dizziness and blurred vision.

  • If you buy any medicines, check with a pharmacist that they are suitable to take with duloxetine. This is because some herbal medicines (such as St John's wort) can increase the risk that you will experience unwanted effects.

  • If you are having an operation or dental treatment, please tell the person carrying out the treatment that you are taking duloxetine.

  • Keep taking duloxetine until your doctor tells you otherwise. Your treatment is likely to last for a number of months.

    • Stopping suddenly can cause symptoms such as headache, sickness, anxiety, dizziness, shakiness and sleeping problems. Your doctor will reduce your dose gradually over a week or two to reduce the risk of these sorts of problems.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה למחלקת תאונות וחירום בבית החולים המקומי שלך. קח את המיכל איתך, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה Yellow Card website.

Does duloxetine cause weight gain?

Duloxetine is not strongly linked with weight gain, however some people may notice changes in their weight. It's important to speak to your doctor if you're concerned.

What is the most common side effect of duloxetine?

The most common side effect of duloxetine is feeling sick (nausea), although other issues like dry mouth or sleep changes can also occur. These side effects often go away over time.

How long can you take duloxetine for nerve pain?

How long you can take duloxetine for nerve pain depends on your individual needs and how well the medicine works for you. Some people may only need it for a few months, while others stay on it longer to keep their symptoms under control.

Is duloxetine addictive?

Duloxetine is not considered addictive. However, stopping it suddenly can cause withdrawal symptoms such as dizziness, headaches, or irritability. For this reason, your doctor will usually advise reducing the dose gradually if you decide to stop.

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