Potassium-aggravated myotonia
עודכן לאחרונה 5 Aug 2021
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Potassium-aggravated myotonia is a disorder that affects muscles used for movement (skeletal muscles). Beginning in childhood or adolescence, people with this condition experience episodes of sustained muscle tensing (myotonia) that prevent muscles from relaxing. Myotonia causes muscle stiffness that worsens after exercise. In this disorder, episodes of myotonia may also be triggered (aggravated) by eating foods that are high in the mineral potassium, such as bananas and potatoes. During these episodes, stiffness occurs in skeletal muscles throughout the body.
תיאור
Potassium-aggravated myotonia is a disorder that affects muscles used for movement (skeletal muscles). Beginning in childhood or adolescence, people with this condition experience episodes of sustained muscle tensing (myotonia) that prevent muscles from relaxing. Myotonia causes muscle stiffness that worsens after exercise. In this disorder, episodes of myotonia may also be triggered (aggravated) by eating foods that are high in the mineral potassium, such as bananas and potatoes. During these episodes, stiffness occurs in skeletal muscles throughout the body.
Potassium-aggravated myotonia ranges in severity from mild episodes of muscle stiffness (myotonia fluctuans) to severe, disabling disease with frequent attacks (myotonia permanen). Unlike some other forms of myotonia, potassium-aggravated myotonia is not associated with episodes of muscle weakness.
Inheritance patterns
The source lists the following possible inheritance patterns: Autosomal dominant. More than one pattern can apply in different cases.
Related genes
Other names
PAM
Sodium channel myotonia
Related patient information and medicines
Patient information leaflet
האם אני יכול לקחת שמן כבד דג וביחד עם אפלרנון?
לוקח cod liver oil and eplerenone together may slightly increase the risk of your blood pressure dropping too low or may affect your potassium levels, though the risk is generally low. Why this happens Cod liver oil contains omega-3 fatty acids, which have a mild blood-pressure-lowering effect... Eplerenone is a medicine specifically designed to.
Patient information leaflet
האם אני יכול לקחת אטנולול ורמיפריל יחד?
This might make you feel dizz... There is also a small risk that the combination could affect your kidney function or increase the levels of potassium in your blood. Why this happens Both medicines work to lower דם pressure but in different ways: atenolol is a beta-blocker that slows the heart rate, while ramipril is an ACE inhibitor that.
Patient information leaflet
האם אני יכול לקחת קנדסארטן וליקסיאנה יחד?
Foods high in Vitamin K (e.g... You can continue to eat spinach, kale, and other leafy greens as normal. Potassium-rich foods (e.g., bananas, spinach, salt substitutes) Candesartan can increase ה levels of potassium in your blood. Consuming large amounts of ואת חשוב מאוד high ב potassium or using potassium-based salt substitutes (such as Lo-Salt).
Patient information leaflet
האם אני יכול לקחת ביסופרולול ורמיפריל יחד?
Food and drink warnings Alcohol Alcohol can increase the blood pressure-lowering effect of bisoprolol, which m... It is best to keep your alcohol intake within recommended limits and see how the medicine affects you before drinking. Salt substitutes (Potassium-based) Ramipril can increase the levels of potassium in your blood. Many salt.
Patient information leaflet
האם אני יכול לקחת נוסטנדי ורמיפריל יחד?
לוקח Nustendi and ramipril together can increase the risk of your kidneys not working as well as they should. It may also lead to high levels of potassium in your blood (hyperkalaemia). Why this happens Nustendi contains two medicines: bempedoic acid and ezetimibe. Bempedoic acid can sometimes increase levels of uric acid and affect kidney.
Patient information leaflet
האם אני יכול לקחת אפלרנון וליקסיאנה יחד?
לוקח eplerenone and Lixiana (edoxaban) together may increase your risk of bleeding. While eplerenone is a diuretic (water tablet) and Lixiana is a blood thinner, they do not have a direct chemical interaction. However, eplerenone can sometimes affect kidney function or potassium levels, which can indirectly influence how your body handles blood.
קריאה נוספת והפניות
- Potassium-aggravated myotonia; MedlinePlus, National Library of Medicine.
- Desaphy JF, Carbonara R, D'Amico A, Modoni A, Roussel J, Imbrici P, Pagliarani S, Lucchiari S, Lo Monaco M, Conte Camerino D. Translational approach to address therapy in myotonia permanens due to a new SCN4A mutation. Neurology. 2016 May 31;86(22):2100-8. doi: 10.1212/WNL.0000000000002721. Epub 2016 Apr 29.
- Lehmann-Horn F, Orth M, Kuhn M, Jurkat-Rott K. A novel N440K sodium channel mutation causes myotonia with exercise-induced weakness--exclusion of CLCN1 exon deletion/duplication by MLPA. Acta Myol. 2011 Oct;30(2):133-7.
- Stunnenberg BC, LoRusso S, Arnold WD, Barohn RJ, Cannon SC, Fontaine B, Griggs RC, Hanna MG, Matthews E, Meola G, Sansone VA, Trivedi JR, van Engelen BGM, Vicart S, Statland JM. Guidelines on clinical presentation and management of nondystrophic myotonias. Muscle Nerve. 2020 Oct;62(4):430-444. doi: 10.1002/mus.26887. Epub 2020 May 27.
- Torbergsen T, Jurkat-Rott K, Stalberg EV, Loseth S, Hodneo A, Lehmann-Horn F. Painful cramps and giant myotonic discharges in a family with the Nav1.4-G1306A mutation. Muscle Nerve. 2015 Oct;52(4):680-3. doi: 10.1002/mus.24672. Epub 2015 Jun 30.
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