pyruvate dehydrogenase E1 subunit beta
עודכן לאחרונה 5 Jul 2022
עומד בהנחיות העריכה של Patient
- הורדהורד
- שתף
- Language
- דיון
- גרסת שמע
- הוסף למקורות מועדפים בגוגל
ה PDHB gene provides instructions for making a protein called E1 beta. E1 beta is a piece (a subunit) of a larger protein: two E1 beta proteins combine with two copies of another protein, called E1 alpha (produced from the PDHA1 gene), to form the E1 enzyme. This enzyme, also known as pyruvate dehydrogenase, is a component of a group of proteins called the pyruvate dehydrogenase complex.
Normal function
ה PDHB gene provides instructions for making a protein called E1 beta. E1 beta is a piece (a subunit) of a larger protein: two E1 beta proteins combine with two copies of another protein, called E1 alpha (produced from the PDHA1 gene), to form the E1 enzyme. This enzyme, also known as pyruvate dehydrogenase, is a component of a group of proteins called the pyruvate dehydrogenase complex.
The pyruvate dehydrogenase complex plays an important role in the pathways that convert the energy from food into a form that cells can use. This complex converts a molecule called pyruvate, which is formed from the breakdown of carbohydrates, into another molecule called acetyl-CoA. The E1 enzyme performs one part of this chemical reaction. The conversion of pyruvate is essential to begin the series of chemical reactions that produces adenosine triphosphate (ATP), the cell's main energy source.
Conditions referring to this gene or chromosome
Other names
ODPB_HUMAN
PDHBD
PDHE1-B
PDHE1B
PHE1B
pyruvate dehydrogenase (lipoamide) beta
pyruvate dehydrogenase E1 component subunit beta, mitochondrial
pyruvate dehydrogenase, E1 beta polypeptide
Related patient information and medicines
Patient information leaflet
האם אני יכול לקחת רויאל סאן ושיטאקה יחד?
Both Royal Sun (Agaricus blazei) and Shiitake (Lentinula edodes) mushrooms contain high levels of beta-glucans, which are substances that stimulate the immune system. Taking them together may cause your immune system to become overactive. General Food Intake These medicinal mushrooms contain complex polysaccharides (beta-glucans). For the best.
Patient information leaflet
התקף לב
ה התקף לב (אוטם שריר הלב) is usually caused by a blood clot, which stops the blood flowing to a part of your heart muscle. You should call for an ambulance immediately if you develop severe chest pain. If someone has a heart attack, treatment with a clot-busting medicine or an emergency procedure to restore the blood flow through the.
Patient information leaflet
האם אני יכול לקחת רויאל סאן וכפתור לבן יחד?
Both Royal Sun (Agaricus blazei) and White Button mushrooms contain compounds that may lower blood sugar levels. Why this happens These mushrooms contain beta-glucans and other compounds that can improve insulin sensitivity or mimic insulin-like effects. They also contain su... General Food Intake These medicinal mushrooms contain complex.
Patient information leaflet
סרטן האשכים
סרטן האשכים מטופל? a cancer that arises from a testicle (testis). Around half of all cases occur in men aged under 35 but testicular cancer rarely occurs before puberty. Another useful test i... The tumour markers commonly tested for are alpha-fetoprotein (AFP), beta human chorionic gonadotrophin (beta-hCG), lactic dehydrogenase (LDH) and.
Patient information leaflet
האם אני יכול לקחת אלוגליפטין וביסופרולול יחד?
It can also slightly increase the risk of your blood sugar dropping too low. Why this happens Bisoprolol is a beta-blocker. These medicines can mask the physical symptoms of low blood sugar, such as a fast heartbeat or tremors. Using other medicines Taking multiple ... Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions,.
Patient information leaflet
האם אני יכול לקחת ביסופרולול וטרימבו יחד?
Bisoprolol and Trimbow (which contains formoterol) work in opposite ways on the airways. Bisoprolol may cause the airways to narrow, making it harder to breathe and potentially triggering asthma or COPD symptoms. It also makes the formoterol in the Trimbow inhaler less effective at opening your airways. Why this happens ביסופרולול is a.
קריאה נוספת והפניות
- pyruvate dehydrogenase E1 subunit beta; MedlinePlus, National Library of Medicine.
- Brown RM, Head RA, Boubriak II, Leonard JV, Thomas NH, Brown GK. Mutations in the gene for the E1beta subunit: a novel cause of pyruvate dehydrogenase deficiency. Hum Genet. 2004 Jul;115(2):123-7. doi: 10.1007/s00439-004-1124-8. Epub 2004 May 11.
- Ganetzky R, McCormick EM, Falk MJ. Primary Pyruvate Dehydrogenase Complex Deficiency Overview. 2021 Jun 17. In: Adam MP, Bick S, Mirzaa GM, Wallace SE, Amemiya A, editors. GeneReviews(R) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2026. Available from http://www.ncbi.nlm.nih.gov/books/NBK571223/
- Okajima K, Korotchkina LG, Prasad C, Rupar T, Phillips JA 3rd, Ficicioglu C, Hertecant J, Patel MS, Kerr DS. Mutations of the E1beta subunit gene (PDHB) in four families with pyruvate dehydrogenase deficiency. Mol Genet Metab. 2008 Apr;93(4):371-80. doi: 10.1016/j.ymgme.2007.10.135. Epub 2008 Mar 4.
- Patel MS, Korotchkina LG, Sidhu S. Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex. J Mol Catal B Enzym. 2009 Nov 1;61(1-2):2-6. doi: 10.1016/j.molcatb.2009.05.001.
הצטרפו לשיחה
שתפו את מחשבותיכם או חוויותיכם עם אחרים ב קהילות המטופלים שלנו.
שאלו, שתפו, התחברו.
עיין בדיונים, שאל שאלות ושתף חוויות במאות נושאים בריאותיים.
הירשמו לניוזלטר של פיישנט
המנה השבועית שלך של עצות בריאות ברורות ואמינות - נכתבה כדי לעזור לך להרגיש מעודכן, בטוח ובשליטה.
על ידי הרשמה אתה מקבל את שלנו מדיניות הפרטיות שלנו. באפשרותך לבטל את המנוי בכל עת. לעולם לא נמכור את הנתונים שלך.