pyruvate dehydrogenase complex component X
עודכן לאחרונה 24 Jun 2021
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ה PDHX gene provides instructions for making a protein called E3 binding protein, which is part of a large group of proteins known as the pyruvate dehydrogenase complex. This complex is made up of several enzymes, including one called E3, and other proteins. E3 binding protein attaches E3 to the complex and provides the correct structure for the complex to perform its function.
Normal function
ה PDHX gene provides instructions for making a protein called E3 binding protein, which is part of a large group of proteins known as the pyruvate dehydrogenase complex. This complex is made up of several enzymes, including one called E3, and other proteins. E3 binding protein attaches E3 to the complex and provides the correct structure for the complex to perform its function.
The pyruvate dehydrogenase complex plays an important role in the pathways that convert the energy from food into a form that cells can use. This enzyme converts a molecule called pyruvate, which is formed from the breakdown of carbohydrates, into another molecule called acetyl-CoA. This conversion is essential to begin the series of chemical reactions that produces adenosine triphosphate (ATP), the cell's main energy source.
Conditions referring to this gene or chromosome
Other names
dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
DLDBP
E3BP
lipoyl-containing pyruvate dehydrogenase complex component X
ODPX_HUMAN
OPDX
proX
pyruvate dehydrogenase complex, component X
pyruvate dehydrogenase complex, E3-binding protein subunit
pyruvate dehydrogenase complex, lipoyl-containing component X
pyruvate dehydrogenase protein X component, mitochondrial
Related patient information and medicines
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האם אני יכול לקחת שיטאקה וזנב הודו יחד?
Why this happens Both mushrooms contain bioactive compounds called beta-glucans. Both alcohol and certain compounds in these mushrooms are processed by the liver; c... General Food Intake These medicinal mushrooms contain complex polysaccharides (beta-glucans). For the best absorption, it is often recommended to take them on an empty stomach, at.
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נוגדי קרישה
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האם אני יכול לקחת זנב הודו וכפתור לבן יחד?
Why this happens Both mushrooms contain bioactive compounds called polysaccharides (such as beta-glucans). Rather than interfering with each other, they may have a complementary effect on the immune system without affecting how the body absorbs or processes eithe... General Food Intake These medicinal mushrooms contain complex polysaccharides.
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אנמיה
Conditions where there are haemoglobin abnormalities such as sickle cell anaemia or thalassaemia - these are discussed below. And problems with the chemicals (or enzymes) that help the blood cell do its job, such as חוסר ב-G6PD ו pyruvate kinase deficiency. Another set of conditions may arise from your immune system attacking your own red.
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האם אני יכול לקחת אמלודיפין ונוסטנדי יחד?
לוקח amlodipine and Nustendi ( ezetimibe ) together can increase the amount of one of the ingredients in Nustendi (bempedoic acid) in your bloodstream. Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see.
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סרטן האשכים
סרטן האשכים is a סרטן that arises from a testicle (testis). Around half of all cases occur in men aged under 35 but testicular cancer rarely occurs before puberty. Another useful test i... The tumour markers commonly tested for are alpha-fetoprotein (AFP), beta human chorionic gonadotrophin (beta-hCG), lactic dehydrogenase (LDH) and.
קריאה נוספת והפניות
- pyruvate dehydrogenase complex component X; MedlinePlus, National Library of Medicine.
- Brown RM, Head RA, Brown GK. Pyruvate dehydrogenase E3 binding protein deficiency. Hum Genet. 2002 Feb;110(2):187-91. doi: 10.1007/s00439-001-0665-3. Epub 2002 Jan 22.
- Brown RM, Head RA, Morris AA, Raiman JA, Walter JH, Whitehouse WP, Brown GK. Pyruvate dehydrogenase E3 binding protein (protein X) deficiency. Dev Med Child Neurol. 2006 Sep;48(9):756-60. doi: 10.1017/S0012162206001617.
- Ganetzky R, McCormick EM, Falk MJ. Primary Pyruvate Dehydrogenase Complex Deficiency Overview. 2021 Jun 17. In: Adam MP, Bick S, Mirzaa GM, Wallace SE, Amemiya A, editors. GeneReviews(R) [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2026. Available from http://www.ncbi.nlm.nih.gov/books/NBK571223/
- Patel MS, Korotchkina LG, Sidhu S. Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex. J Mol Catal B Enzym. 2009 Nov 1;61(1-2):2-6. doi: 10.1016/j.molcatb.2009.05.001.
- Smolle M, Prior AE, Brown AE, Cooper A, Byron O, Lindsay JG. A new level of architectural complexity in the human pyruvate dehydrogenase complex. J Biol Chem. 2006 Jul 14;281(28):19772-80. doi: 10.1074/jbc.M601140200. Epub 2006 May 5.
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