RUNX1 partner transcriptional co-repressor 1
עודכן לאחרונה 5 Jul 2022
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ה RUNX1T1 gene provides instructions for making a protein commonly referred to as ETO, which helps regulate the activity of genes. ETO is considered a transcriptional corepressor because it turns off (represses) gene activity. It performs this function by attaching (binding) to proteins that normally turn genes on and blocking their activity. It also interacts with other corepressors to help keep genes turned off.
Normal function
ה RUNX1T1 gene provides instructions for making a protein commonly referred to as ETO, which helps regulate the activity of genes. ETO is considered a transcriptional corepressor because it turns off (represses) gene activity. It performs this function by attaching (binding) to proteins that normally turn genes on and blocking their activity. It also interacts with other corepressors to help keep genes turned off.
Conditions referring to this gene or chromosome
Other names
acute myelogenous leukemia 1 translocation 1, cyclin-D related
AML1T1
CBFA2T1
CDR
core-binding factor, runt domain, alpha subunit 2; translocated to, 1; cyclin D-related
eight twenty one protein
ETO
MTG8
MTG8_HUMAN
myeloid translocation gene on 8q22
protein CBFA2T1
runt related transcription factor 1; translocated to, 1 (cyclin D related)
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
zinc finger MYND domain-containing protein 2
ZMYND2
Related patient information and medicines
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Taking co-amoxiclav and ramipril together can occasionally increase the risk of a rare but serious allergic reaction called angioedema (swelling under the skin). Our Medicines Interaction Checker helps אתה check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. הבהרה This information is for.
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שיטות מניעה
However, no method is completely (100%) reliable. The reliability for each method is given in percentages, or in numbers of women per 100 women. If the method fails in less than 1 in 100 women, the number of women who fall pregnant may be given per 1,000 women. For example, the contraceptive injection is more than 99% effective. In other words it.
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האם אני יכול לקחת אטנולול וקו-אמוקסיקלב יחד?
למה זה קורה אתנולול מטופל? a beta-blocker used for heart conditions and blood pressure, while קו-אמוקסיקלב מטופל? a combination antibiotic (amoxicillin and clavulanic acid). Our Medicines Interaction Checker helps אתה check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Disclaimer This information.
קריאה נוספת והפניות
- RUNX1 partner transcriptional co-repressor 1; MedlinePlus, National Library of Medicine.
- Goyama S, Mulloy JC. Molecular pathogenesis of core binding factor leukemia: current knowledge and future prospects. Int J Hematol. 2011 Aug;94(2):126-133. doi: 10.1007/s12185-011-0858-z. Epub 2011 May 3.
- Guo C, Hu Q, Yan C, Zhang J. Multivalent binding of the ETO corepressor to E proteins facilitates dual repression controls targeting chromatin and the basal transcription machinery. Mol Cell Biol. 2009 May;29(10):2644-57. doi: 10.1128/MCB.00073-09. Epub 2009 Mar 16.
- Lam K, Zhang DE. RUNX1 and RUNX1-ETO: roles in hematopoiesis and leukemogenesis. Front Biosci (Landmark Ed). 2012 Jan 1;17(3):1120-39. doi: 10.2741/3977.
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