Can I take Amlodipine and Danazol together?

למה זה קורה

Amlodipine is broken down in the liver by a specific enzyme (CYP3A4). Danazol interferes with this process by blocking the enzyme, which means the amlodipine stays in your system longer and reaches higher levels than normal.

You should speak to your doctor before taking these two medicines together. Your doctor may need to monitor your blood pressure more closely or adjust your dose of amlodipine while you are taking danazol. If you feel unusually dizzy or faint, contact your healthcare provider.

הריון

You must not take danazol if you are pregnant or planning to become pregnant. It can cause the development of male physical characteristics in a female fetus. You must use effective, non-hormonal contraception (such as condoms) while taking it.

Grapefruit juice consumption

Avoid drinking large amounts of grapefruit juice. Grapefruit can increase the level of amlodipine in your blood, which may cause your blood pressure to drop too low.

Blood clots and stroke

Danazol significantly increases the risk of serious blood clots and can cause increased pressure inside the skull. Seek immediate medical help if you experience severe headaches, blurred vision, or sudden leg swelling.

מיץ אשכוליות

Grapefruit juice can increase the amount of amlodipine in your blood, which may cause your blood pressure to drop too low and increase the risk of side effects like headaches or swelling. Avoid drinking large amounts of grapefruit juice.

אלכוהול

While alcohol does not have a direct interaction, both alcohol and amlodipine can lower your blood pressure. Drinking alcohol while taking this medicine may make you feel dizzy, lightheaded, or faint.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.