Can I take Candesartan and Eplerenone together?

למה זה קורה

Both candesartan and eplerenone work by affecting a hormone system in the body that regulates salt and water balance. Specifically, they both cause the kidneys to keep hold of potassium rather than flushing it out in the urine. When used together, this 'potassium-sparing' effect is doubled.

You must speak to your doctor before taking these together. If prescribed both, your doctor will need to monitor your kidney function and potassium levels very closely with regular blood tests. Seek medical help immediately if you experience muscle weakness, tingling sensations, or an irregular heartbeat. Avoid using salt substitutes containing potassium (such as Lo-Salt) while taking these medicines.

הריון

You must not take these medicines if you are pregnant or planning to become pregnant. They can cause serious harm or death to an unborn baby, particularly if used during the second and third trimesters.

High potassium levels (Hyperkalaemia)

Both medicines increase potassium levels in your blood. You must avoid using potassium supplements or salt substitutes containing potassium, as dangerously high levels can cause life-threatening heart rhythm problems.

Kidney function and NSAID use

Taking anti-inflammatory painkillers (like ibuprofen or naproxen) while on these medicines can significantly increase the risk of sudden kidney failure. Check with a pharmacist before using any over-the-counter pain relief.

אלכוהול

Drinking alcohol while taking these medicines can cause your blood pressure to drop too low. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep your alcohol intake within recommended limits and see how the medicine affects you first.

מיץ אשכוליות

You should avoid drinking large amounts of grapefruit juice. Grapefruit contains compounds that can increase the level of eplerenone in your blood, which may increase the risk of side effects.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.