Can I take Danazol and Tramadol together?

למה זה קורה

Tramadol is broken down in the liver by specific enzymes. Danazol blocks these enzymes, preventing the body from clearing the tramadol. This leads to a build-up of the painkiller to potentially toxic levels.

You should speak to your doctor before taking these two medicines together. Your doctor may need to adjust your dose of tramadol or monitor you more closely for side effects. If you feel unusually dizzy, sleepy, or have trouble breathing, seek medical help immediately.

הריון

You must not take danazol if you are pregnant or planning to become pregnant. It can cause the development of male physical characteristics in a female fetus. You must use effective, non-hormonal contraception (such as condoms) while taking it.

Blood clots (Thromboembolism)

Danazol significantly increases the risk of serious blood clots. Seek immediate medical help if you experience sudden leg swelling, chest pain, or shortness of breath.

Liver disease

Danazol can cause serious liver damage and non-cancerous liver tumours. You will need regular blood tests to monitor your liver function while taking this medicine.

אפילפסיה או היסטוריה של התקפים

Tramadol can increase the risk of having a fit (seizure), even at the recommended dose. This risk is higher if you already have epilepsy or are taking certain antidepressants.

אסתמה או בעיות נשימה

Tramadol can cause dangerous breathing difficulties (respiratory depression). You must not take it if you have severe asthma or significant breathing problems.

אלכוהול

It is best to avoid or strictly limit alcohol while taking danazol. Combining danazol with alcohol can cause you to feel nauseous or short of breath (a disulfiram-like reaction). Additionally, both danazol and alcohol can put strain on your liver, and using them together increases the risk of liver damage.

It is best to avoid or strictly limit alcohol while taking tramadol. Combining alcohol with tramadol significantly increases the risk of dangerous side effects, such as extreme sleepiness, breathing difficulties, and loss of consciousness.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.