Can I take Evolocumab and Furosemide together?

למה זה קורה

Evolocumab is a monoclonal antibody that helps the liver remove cholesterol from the blood. Furosemide is a diuretic (water tablet) that helps the kidneys remove excess salt and water. These medicines are processed by different pathways in the body and do not overlap in their actions.

You can safely take these two medicines together as prescribed by your doctor. No special precautions or dose changes are needed. Always inform your healthcare provider of all medications you are taking, including over-the-counter supplements.

Dehydration and low blood pressure

Furosemide is a potent diuretic. You must not take it if you are already severely dehydrated or cannot pass urine. It can cause a rapid drop in blood pressure and salt levels, especially if you are also taking other blood pressure medicines.

Gout

Furosemide can increase the levels of uric acid in your blood, which may trigger a painful gout attack or make existing gout worse.

Latex allergy - evolocumab

The needle cover of the pre-filled syringe/pen contains dry natural rubber (a derivative of latex), which may cause severe allergic reactions in people with a sensitive latex allergy.

אלכוהול

It is best to avoid or strictly limit alcohol while taking furosemide. Both alcohol and furosemide can lower your blood pressure and have a diuretic effect (making you pee more). Combining them increases the risk of dizziness, lightheadedness, or fainting, especially when standing up. It can also lead to dehydration.

It is best to avoid or strictly limit alcohol while taking evolocumab. Combining alcohol with cholesterol-lowering treatments can increase the risk of liver strain or damage.

Liquorice (Natural) / Liquorice Root

Avoid eating large amounts of natural liquorice or taking liquorice root supplements. Natural liquorice can cause the body to lose potassium and retain salt, which opposes the action of furosemide and can lead to dangerously low potassium levels.

קפאין (קפה, תה, משקאות אנרגיה)

Limit your intake of caffeine. Caffeine is a mild diuretic and can increase the water-loss effect of furosemide, potentially increasing the risk of dehydration or electrolyte imbalances.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.