Can I take Lercanidipine and Promethazine together?

למה זה קורה

Lercanidipine works by relaxing your blood vessels to lower blood pressure. Promethazine, while primarily an antihistamine, can also cause blood vessels to widen slightly and has a sedating effect on the brain. When combined, these effects add together, increasing the risk of low blood pressure and sleepiness.

You should use caution when taking these medicines together. Monitor your blood pressure regularly and be careful when getting out of bed or standing up. If you feel very dizzy or sleepy, avoid driving or operating machinery. If you experience fainting or severe dizziness, contact your doctor to see if your doses need adjusting.

Breathing problems (e.g. asthma, COPD, sleep apnoea)

Promethazine can cause severe breathing difficulties and should be avoided if you have serious lung disease or breathing problems, as it can suppress your respiratory system. Promethazine must not be given to children under 2 years of age because it can cause life-threatening breathing difficulties (respiratory depression).

Glaucoma or prostate issues

Promethazine can worsen symptoms of narrow-angle glaucoma (increasing eye pressure) or cause sudden inability to pass urine if you have an enlarged prostate.

Drowsiness and safety-critical tasks

Promethazine causes significant drowsiness that can last into the next day. Do not drive or operate machinery if you feel sleepy or if your alertness is impaired.

Severe liver or kidney disease

Lercanidipine is not recommended if you have severe liver or kidney problems. Ensure your doctor is aware of your condition before starting treatment.

אלכוהול

It is best to avoid or strictly limit alcohol while taking these medicines. For lercanidipine, alcohol can increase the blood-pressure-lowering effect, making you feel dizzy or faint. For promethazine, alcohol increases the sedative effect, making you dangerously drowsy and increasing the risk of breathing difficulties.

אשכולית ומיץ אשכוליות

You must not eat grapefruit or drink grapefruit juice while taking lercanidipine. Grapefruit can significantly increase the amount of the medicine in your blood, making side effects like dizziness, headaches, and a fast heartbeat much more likely.

ארוחות עתירות שומן

Lercanidipine should be taken at least 15 minutes before a meal. Taking it with or immediately after a high-fat meal can significantly increase the amount of medicine absorbed by your body, which may lead to more side effects.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.