Idiopathic inflammatory myopathy
עודכן לאחרונה 22 Dec 2025
עומד בהנחיות העריכה של Patient
- הורדהורד
- שתף
- Language
- דיון
- גרסת שמע
- הוסף למקורות מועדפים בגוגל
Idiopathic inflammatory myopathy is a group of disorders characterised by inflammation of the muscles used for movement (skeletal muscles). Idiopathic inflammatory myopathy usually appears in adults between ages 40 and 60 or in children between ages 5 and 15, though it can occur at any age.
תיאור
Idiopathic inflammatory myopathy is a group of disorders characterised by inflammation of the muscles used for movement (skeletal muscles). Idiopathic inflammatory myopathy usually appears in adults between ages 40 and 60 or in children between ages 5 and 15, though it can occur at any age.
The primary symptom of idiopathic inflammatory myopathy is muscle weakness, which develops gradually over a period of weeks to months or even years. Other symptoms include joint pain and general tiredness (fatigue).
There are several forms of idiopathic inflammatory myopathy, including polymyositis, dermatomyositis, and sporadic inclusion body myositis.
Polymyositis and dermatomyositis involve weakness of the muscles closest to the center of the body (proximal muscles), such as the muscles of the hips and thighs, upper arms, and neck. People with these forms of idiopathic inflammatory myopathy may find it difficult to climb stairs, get up from a seated position, or lift items above their head. In some cases, muscle weakness may make swallowing or breathing difficult.
Polymyositis and dermatomyositis have similar symptoms, but dermatomyositis is distinguished by a reddish or purplish rash on the eyelids, elbows, knees, or knuckles. Sometimes, abnormal calcium deposits form hard, painful bumps under the skin (calcinosis).
In sporadic inclusion body myositis, the muscles most affected are those of the wrists and fingers and the front of the thigh. Affected individuals may frequently stumble while walking and find it difficult to grasp items. As in dermatomyositis and polymyositis, swallowing can be difficult.
Inheritance patterns
The source lists the following possible inheritance patterns: Pattern unknown. More than one pattern can apply in different cases.
Related genes
Other names
Idiopathic inflammatory myopathies
Idiopathic inflammatory myositis
Inflammatory myopathy, idiopathic
Related patient information and medicines
Patient information leaflet
אובאיטיס
אובאיטיס is a general term describing inflammation of the part of the eye called the uveal tract. However, in up to half of cases, no specific cause is found. This is known as idiopathic uveitis. The known causes and associations of uveitis include the following: Autoimmune and inflammatory diseases Our immune system normally makes small proteins.
Patient information leaflet
אריתמה נודוזום
אריתמה נודוזום is a condition that causes red rounded lumps (nodules) to form just below the skin surface, most commonly on the shins. In most people, no specific cause or trigger can be found. But in some people a trigger (commonly a streptococ... In over half of people who develop erythema nodosum, no cause for the inflammation is found..
Patient information leaflet
פריקרדיטיס
פריקרדיטיס מטופל? דלקת of the pericardium, which is the sac which surrounds and helps to protect the heart. Inflammatory diseases which can affect various parts of the body may include דלקת of the pericardium - למשל, rheumatoid arthritis , scleroderma , polyarteritis nodosa ו systemic lupus erythematosus (SLE). This is.
Patient information leaflet
התכווצויות ברגליים
What causes leg cramps. Unknown cause (idiopathic leg cramps) In most cases the cause is not known. One theory is that cramps occur when a muscle that is already in a shortened position is stimulated to contract. As the muscle is already shortened, to contract further may caus... Excess alcohol. Rare causes which include 'scarring' of the כבד (.
Patient information leaflet
האם אני יכול לקחת אמלודיפין וסימבסטטין יחד?
Taking these two medicines together can increase the amount of simvastatin in your blood. This makes you more likely to experience side effects, particularly muscle pain, tenderness, or weakness (a condition called myopathy). In rare cases, this can lead to a serious condition called rhabdomyolysis, which can cause kidney damage. Why this happens.
Patient information leaflet
האם אני יכול לקחת אטורבסטטין ותמצית גדילן מצוי יחד?
Taking milk thistle with atorvastatin might increase the levels of the medication in your bloodstream. This could potentially increase the risk of side effects, such as muscle aches, pain, or weakness (a condition called myopathy). Caution is advised when taking atorvastati and milk thistle together. Combining them may increase the amount of.
קריאה נוספת והפניות
- Idiopathic inflammatory myopathy; MedlinePlus, National Library of Medicine.
- Chinoy H, Lamb JA, Ollier WE, Cooper RG. An update on the immunogenetics of idiopathic inflammatory myopathies: major histocompatibility complex and beyond. Curr Opin Rheumatol. 2009 Nov;21(6):588-93. doi: 10.1097/BOR.0b013e3283315a22.
- Chinoy H, Platt H, Lamb JA, Betteridge Z, Gunawardena H, Fertig N, Varsani H, Davidson J, Oddis CV, McHugh NJ, Wedderburn LR, Ollier WE, Cooper RG; UK Adult Onset Myositis Immunogenetic Collaboration and the Juvenile Dermatomyositis Research Group. The protein tyrosine phosphatase N22 gene is associated with juvenile and adult idiopathic inflammatory myopathy independent of the HLA 8.1 haplotype in British Caucasian patients. Arthritis Rheum. 2008 Oct;58(10):3247-54. doi: 10.1002/art.23900.
- Cox S, Limaye V, Hill C, Blumbergs P, Roberts-Thomson P. Idiopathic inflammatory myopathies: diagnostic criteria, classification and epidemiological features. Int J Rheum Dis. 2010 May;13(2):117-24. doi: 10.1111/j.1756-185X.2010.01472.x.
- O'Hanlon TP, Carrick DM, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Dreyfuss J, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Plotz PH, Love LA, Miller FW. Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1 and -DQA1 allelic profiles and motifs define clinicopathologic groups in caucasians. Medicine (Baltimore). 2005 Nov;84(6):338-349. doi: 10.1097/01.md.0000189818.63141.8c.
- Rider LG, Miller FW. Deciphering the clinical presentations, pathogenesis, and treatment of the idiopathic inflammatory myopathies. JAMA. 2011 Jan 12;305(2):183-90. doi: 10.1001/jama.2010.1977.
- Shamim EA, Miller FW. Familial autoimmunity and the idiopathic inflammatory myopathies. Curr Rheumatol Rep. 2000 Jun;2(3):201-11. doi: 10.1007/s11926-000-0080-0.
- Shamim EA, Rider LG, Miller FW. Update on the genetics of the idiopathic inflammatory myopathies. Curr Opin Rheumatol. 2000 Nov;12(6):482-91. doi: 10.1097/00002281-200011000-00002.
הצטרפו לשיחה
שתפו את מחשבותיכם או חוויותיכם עם אחרים ב קהילות המטופלים שלנו.
שאלו, שתפו, התחברו.
עיין בדיונים, שאל שאלות ושתף חוויות במאות נושאים בריאותיים.
הירשמו לניוזלטר של פיישנט
המנה השבועית שלך של עצות בריאות ברורות ואמינות - נכתבה כדי לעזור לך להרגיש מעודכן, בטוח ובשליטה.
על ידי הרשמה אתה מקבל את שלנו מדיניות הפרטיות שלנו. באפשרותך לבטל את המנוי בכל עת. לעולם לא נמכור את הנתונים שלך.