Can I take Atorvastatin and Milk thistle extract together?

Caution is advised when taking atorvastati and milk thistle together. Combining them may increase the amount of atorvastatin in your system, increasing the risk of atorvastatin side effects.

למה זה קורה

Milk thistle contains a compound called silymarin. Silymarin can interfere with certain proteins (transporters) and enzymes in the liver that are responsible for breaking down and removing atorvastatin from your body.

If the liver cannot process the statin as quickly as usual, the drug levels can rise.

• Use caution if combining these two medicines.

• If you decide to take milk thistle, monitor yourself closely for any new or unusual muscle pain, tenderness, or weakness, as well as any yellowing of the skin or eyes (jaundice).

• It is best to inform your doctor or pharmacist before starting milk thistle so they can ensure your statin dose remains appropriate for you.

הריון

אסור לך לקחת אטורבסטטין אם את בהריון או מתכננת להיכנס להריון, שכן זה יכול לגרום לנזק חמור לעובר. השתמשי באמצעי מניעה יעילים בזמן נטילת תרופה זו.

Muscle disorders - atorvastatin

You must report any unexplained muscle pain, tenderness, or weakness to your doctor immediately, as this can rarely lead to serious kidney damage.

Hormone-sensitive conditions

Avoid milk thistle if you have a history of hormone-sensitive cancers or conditions (such as breast cancer or endometriosis), as it may have oestrogen-like effects that could worsen these conditions.

מיץ אשכוליות

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This can increase your risk of side effects, such as muscle pain or liver problems.

You should avoid drinking large quantities (more than 1.2 litres daily), but it is safest to avoid it altogether while taking this medicine.

אלכוהול

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver damage and may raise triglyceride levels, which can counteract the benefits of the medicine.

It is advised to keep alcohol intake within recommended limits.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.