Can I take Atorvastatin and Lansoprazole together?

Why this happens

Lansoprazole reduces stomach acid, but this does not significantly change how atorvastatin is absorbed or processed by the liver. They are broken down by different pathways in the body.

What you should do

You can safely take these medicines together. You do not need to change the timing of your doses unless your doctor has given you specific instructions. Always follow the dosage on your prescription labels.

Important precautions

Pregnancy

You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking this medicine.

Muscle disorders - atorvastatin

Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.

Severe diarrhoea

If you develop severe or persistent watery diarrhoea, seek medical advice promptly, as lansoprazole can increase the risk of serious bowel infections like Campylobacter or C. difficile.

Food and drink warnings

Grapefruit juice

Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.

Alcohol

While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits (no more than 14 units per week).

Food (Timing)

Lansoprazole works best if you take it at least 30 minutes before a meal. Taking it with food can make it less effective at reducing stomach acid.

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.