Can I take Atorvastatin and White button together?
Drug interaction guide
Originally published 25 Jan 2026
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There is no known interaction between atorvastatin and white button mushrooms (Agaricus bisporus). In fact, some studies suggest that white button mushrooms may have a beneficial effect on cholesterol levels, though they are not a replacement for your prescribed medication.
Why this happens
White button mushrooms do not affect the liver enzymes (specifically CYP3A4) that break down atorvastatin, nor do they interfere with how the drug is absorbed or excreted by the body.
What you should do
You can safely eat white button mushrooms while taking atorvastatin. Continue to take your medication as prescribed by your doctor. If you are considering taking concentrated mushroom supplements or powders, it is always best to check with your pharmacist first, as these are much stronger than culinary mushrooms.
Important precautions
Pregnancy
You must not take atorvastatin if you are pregnant or planning to become pregnant, as it can cause serious harm to an unborn baby. Use effective contraception while taking this medicine.
Muscle disorders - atorvastatin
Seek immediate medical advice if you experience unexplained muscle pain, tenderness, or weakness. In rare cases, this can lead to a serious condition called rhabdomyolysis which causes kidney damage.
Food and drink warnings
Grapefruit juice
Grapefruit juice contains compounds that can increase the level of atorvastatin in your blood. This may increase your risk of side effects, such as muscle pain or damage. Avoid drinking large quantities (more than 1.2 litres per day), though it is safest to avoid it altogether or keep intake to very small amounts.
Alcohol
While alcohol does not directly interact with atorvastatin, drinking large amounts of alcohol can increase the risk of liver problems and muscle side effects. It is best to keep your intake within the recommended limits (no more than 14 units per week).
Using other medicines
Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.
Disclaimer
This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.
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Article history
The information on this page is written and peer reviewed by qualified clinicians.
Article also available in English, German, Spanish, French, Italian, Portuguese, Hindi, Hebrew, Arabic, and Swedish.
25 Jan 2026 | Originally published
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