Can I take Felodipine and Grapefruit together?

You must completely avoid grapefruit and grapefruit juice while taking felodipine. Grapefruit significantly increases the amount of felodipine in your blood, which can cause your blood pressure to drop dangerously low and increase the risk of side effects.

Even a single glass of juice or half a grapefruit can significantly increase the amount of the medicine in your bloodstream, and the impact can last for several days.

If you have already consumed grapefruit, monitor your blood pressure and watch for dizziness or a racing heart.

Speak to your doctor or pharmacist about safe fruit alternatives, such as oranges or lemons.

למה זה קורה

Your body uses a specific enzyme (called CYP3A4) in the gut and liver to break down felodipine. Grapefruit contains natural compounds that block this enzyme. When the enzyme is blocked, your body cannot clear the medicine properly, leading to much higher levels of the drug than intended.

You may be experiencing an interaction between felodipine and grapefruit (including grapefruit juice) if:

• You feel dizzy or lightheaded, especially when standing up.

• You experience headaches or flushing.

• You notice swelling in your ankles or feet.

• You feel your heart beating faster than usual (דפיקות לב).

• You develop low blood pressure symptoms, such as faintness or weakness.

• Symptoms start after eating grapefruit or drinking grapefruit juice while taking felodipine.

If you have any of the above symptoms, you should:

• Speak to your GP or pharmacist for advice as soon as possible.

• Avoid grapefruit and grapefruit juice while taking felodipine.

• Do not stop taking felodipine suddenly unless advised by a healthcare professional.

• Seek urgent medical help if you faint or have severe dizziness.

• Attend any blood pressure checks arranged to monitor your treatment.
  

אלכוהול

Drinking alcohol while taking felodipine can increase the blood-pressure-lowering effect of the medicine. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep your alcohol intake to a minimum.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.