האם אני יכול לקחת גליבנקלאמיד ואמפגליפלוזין יחד?

למה זה קורה

Both medicines work to lower blood sugar but in different ways. Glibenclamide stimulates the pancreas to release more insulin, while empagliflozin helps the kidneys remove sugar through urine. When used together, their effects add up, which can lower blood sugar more than intended. Additionally, both can have a mild diuretic effect, increasing the risk of fluid loss.

You must speak to your doctor before taking these together. Your doctor may need to reduce your dose of glibenclamide to prevent your blood sugar from dropping too low. Ensure you know how to recognise and treat a 'hypo' (shaking, sweating, hunger, irritability) and drink plenty of water to stay hydrated.

Diabetic Ketoacidosis (DKA)

Empagliflozin can cause a serious condition called ketoacidosis even if your blood sugar levels are near normal. You must seek urgent medical help if you experience nausea, vomiting, abdominal pain, or fruity-smelling breath. Stop taking this medicine if you are fasting for surgery or have a severe illness.

היפוגליקמיה (רמת סוכר נמוכה בדם)

Glibenclamide carries a high risk of severe, prolonged low blood sugar (hypoglycaemia). You must carry sugar with you at all times. Be aware that this risk is significantly higher in older people or those with kidney problems.

Fournier’s Gangrene

Seek immediate medical attention if you experience pain, tenderness, redness, or swelling in the genital or anal area, accompanied by fever or malaise. This could be a sign of a rare but life-threatening infection.

אלכוהול

Drinking alcohol while taking these medicines can increase the risk of low blood sugar (hypoglycaemia). Alcohol can also mask the warning signs of a 'hypo'. Additionally, for empagliflozin, excessive alcohol consumption can increase the risk of a rare but serious condition called ketoacidosis. You should limit your alcohol intake and avoid drinking on an empty stomach.

Taking multiple medicines? Our בודק אינטראקציות בין תרופות helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

הבהרה

מידע זה מיועד למטרות חינוכיות כלליות בלבד ואין להסתמך עליו כתחליף לייעוץ רפואי מקצועי. תמיד יש להתייעץ עם רופא המשפחה, רוקח או איש מקצוע רפואי מוסמך אחר לפני קבלת החלטות לגבי התרופות שלך. נסיבות אישיות עשויות להשתנות, ורק איש מקצוע רפואי שמכיר את ההיסטוריה הרפואית שלך יכול לספק הנחיות מותאמות אישית.