דלג לתוכן הראשי

Prasugrel tablets

Efient

You will be given six 10 mg tablets to take as your first dose. After this, take one tablet daily.

The most common unwanted effect is an increased risk of bleeding. It is important that you let your doctor know if you notice any unusual or unexpected bleeding or bruising.

If you need to take any painkillers, check with your doctor or pharmacist that they are suitable for you. Some painkillers interact with prasugrel.

At a glance

  • Prasugrel is an antiplatelet medicine that helps stop blood clots forming.

  • It is taken after a procedure to open a blocked artery in the heart (PCI), often with a stent.

  • You will also take aspirin alongside prasugrel.

  • Tell your doctor if you are pregnant, breastfeeding, or have a bleeding condition.

  • You will take six tablets for the first dose, then one tablet daily.

  • Prasugrel can cause bleeding, bruising, or nosebleeds.

  • Tell your doctor or pharmacist if you experience any side-effects.

המשך לקרוא למטה

About prasugrel tablets

סוג התרופה

תרופה נוגדת טסיות

שימוש עבור

To prevent clots forming in blood vessels after a procedure called percutaneous coronary intervention (to open a blocked artery in the heart or for a stent insertion)

נקרא גם

Efient®

זמין כ

טבליות

In your blood there are 'sticky' cells called platelets. When you cut yourself, the platelets stick to each other (clot) to seal the wound. Sometimes platelets stick to each other inside an artery - this is called a thrombus. If a thrombus forms in a blood vessel around your heart, this reduces the flow of blood to your heart. The term acute coronary syndrome (ACS) covers a range of disorders that are caused by this underlying problem, and include התקפי לב and a type of chest pain known as unstable angina.

If you require a procedure to open a blocked artery in your heart because you have already had a heart attack or because you have unstable angina, you will be prescribed an antiplatelet medicine like prasugrel during the procedure.

For some people with ACS, the most appropriate treatment is to have a stent inserted into the blocked or narrowed artery to restore the flow of blood. A stent is like a wire mesh tube which gives support to the blood vessel. After a stent has been inserted, antiplatelet medicines are given routinely. These medicines reduce the stickiness of platelets, and this helps prevent the platelets from sticking to the inside of the artery and going on to form a further clot (thrombus).

Prasugrel is one of these antiplatelet medicines. Your doctor will also prescribe aspirin for you to take alongside prasugrel. Aspirin is another antiplatelet medicine.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking prasugrel tablets it is important that your doctor knows:

  • אם את בהריון או מניקה.

  • אם יש לך בעיות בתפקוד הכבד שלך, או אם יש לך בעיות בתפקוד הכליות שלך.

  • If you have ever had a stroke, or a transient ischaemic attack (sometimes called a TIA or 'mini-stroke').

  • If you have a condition which causes bleeding, such as a recent wound or a stomach ulcer.

  • If you have ever had an allergic reaction to a medicine, particularly if you have had a bad reaction to any other antiplatelet medicine (for example, clopidogrel).

  • אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

המשך לקרוא למטה

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about prasugrel, and it will also provide you with a full list of the side-effects which you could experience from taking it.

  • Take the tablets exactly as your doctor tells you to. On the first day of treatment, you will be given six 10 mg tablets (60 mg) to take so that you get sufficient medicine into your bloodstream to begin with. After this, you will be prescribed one tablet to take each day. For most people, the tablets will contain 10 mg prasugrel, although depending upon your body weight you could be prescribed the lower 5 mg strength tablet.

  • Swallow the tablets with a drink of water - do not crush or chew the tablets as you swallow. You can take prasugrel tablets either with or without food.

  • Try to take your doses around the same time of day, each day. This will help you to remember to take prasugrel regularly.

  • אם שכחת לקחת מנה, קח אותה ברגע שאתה נזכר. אם אינך נזכר עד ליום המחרת, דלג על המנה שנשכחה מהיום הקודם וקח את המנה המיועדת כרגיל. אל תיקח שתי מנות באותו זמן כדי לפצות על מנה שנשכחה.

  • Try to keep all your regular appointments with your doctor. This is so your doctor can check on your progress. It is likely you will require a course of treatment with prasugrel which lasts for up to 12 months.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take with prasugrel tablets. Some medicines, called non-steroidal anti-inflammatory drugs (NSAIDs), can increase the risk of bleeding, so check with a pharmacist before you buy any painkillers. Also, do not take any preparations containing aspirin that have not been prescribed for you by your doctor. Several medicines for pain relief and cold relief that can be bought at retail outlets contain aspirin or ibuprofen - you should not take these, so check the label carefully before you buy.

  • If you are due to have an operation, before the treatment is due, tell the person carrying out the treatment that you are taking prasugrel. This is because any bleeding may take longer than normal to stop so your treatment may need to be interrupted for a short while before the operation. You should also let your dentist know that you are taking prasugrel before you receive any dental treatment.

המשך לקרוא למטה

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the more common ones associated with prasugrel. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common prasugrel side-effects (these affect fewer than 1 in 10 people)


מה אני יכול לעשות אם אני חווה את זה?

Bleeding, bruising, nosebleeds. Stopping bleeding could take longer than normal

Let your doctor know if you notice any unusual or unexpected bleeding or bruising

Skin rash, feeling tired (due to anaemia)

Let your doctor know, especially if it is severe or troublesome

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהטבליות, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה למחלקת תאונות וחירום בבית החולים המקומי שלך. קח את המיכל איתך, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה Yellow Card website.

symptom checker

לא בטוחים לגבי ערבוב תרופות?

בדוק אינטראקציות אפשריות בין תרופות, תוספים ומזונות לפני נטילתם יחד.

שאלות נפוצות

What specifically is a percutaneous coronary intervention and why do I need prasugrel afterwards?

A percutaneous coronary intervention is a procedure to open a blocked artery in your heart. This could be to address a heart attack, unstable angina, or if a stent is inserted into a blocked or narrowed artery. You will be prescribed prasugrel afterwards because it is an antiplatelet medicine that reduces the stickiness of platelets, helping to prevent them from forming further clots on the inside of the artery or around the stent.

How long will I need to take prasugrel tablets?

It is likely you will need to continue treatment with prasugrel for a course that lasts up to 12 months. Your doctor will monitor your progress and advise you on the exact duration of your treatment.

What should I do if I accidentally take two doses of prasugrel?

If you suspect that you or someone else might have taken an overdose of this medicine, you should go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you, even if it is empty.

Are there any specific painkillers I should avoid while taking prasugrel?

Yes, you should avoid certain painkillers. Some medicines, known as non-steroidal anti-inflammatory drugs (NSAIDs), can increase your risk of bleeding when taken with prasugrel. You should also not take any preparations containing aspirin that haven't been prescribed by your doctor. Many over-the-counter pain relief and cold relief medicines contain either aspirin or ibuprofen, which are NSAIDs, so always check the label carefully or ask a pharmacist before buying any.

Why is it important to tell my dentist that I'm taking prasugrel?

It's important to inform your dentist that you are taking prasugrel before any dental treatment begins. This is because prasugrel can make any bleeding take longer than normal to stop. Your dentist will need to be aware of this to take appropriate precautions.

What should I do if I notice unusual bleeding or bruising while on prasugrel?

Prasugrel can cause bleeding, bruising, and nosebleeds, and stopping bleeding might take longer than usual. If you notice any unusual or unexpected bleeding or bruising that seems severe or troublesome, you should let your doctor know.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

הלן אלן, MPharm

Pharmacist, Medical Author

MPharm

Helen Allen qualified as a Pharmacist in 1979 and spent 3 years as the drug information leaflets' author for EMIS.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • הסקירה הבאה מתוכננת ל: 8 יולי 2027
  • 9 Jan 2023 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
  • 10 Sept 2013 | פורסם במקור

    נכתב על ידי:

    הלן אלן, MPharm
flu eligibility checker

שאלו, שתפו, התחברו.

עיין בדיונים, שאל שאלות ושתף חוויות במאות נושאים בריאותיים.

הירשמו לניוזלטר של פיישנט

המנה השבועית שלך של עצות בריאות ברורות ואמינות - נכתבה כדי לעזור לך להרגיש מעודכן, בטוח ובשליטה.

אנא הזן כתובת דוא"ל תקינה

By subscribing you accept our מדיניות הפרטיות שלנו. באפשרותך לבטל את המנוי בכל עת. לעולם לא נמכור את הנתונים שלך.