Can I take Ashwagandha and Ramipril together?

You should speak with your doctor before taking ashwagandha and ramipril together as they may cause your blood pressure to drop lower than intended.

If you do take both, monitor your blood pressure regularly at home and watch for signs of low blood pressure (hypotension). If you feel very dizzy or faint, stop taking the supplement and contact your doctor.

Why this happens

Both substances lower blood pressure. Ramipril is an ACE inhibitor designed to relax blood vessels. Ashwagandha has natural sedative and blood-pressure-lowering properties.

When used together, their effects can add up (an additive effect), potentially making your blood pressure too low.

How to know if you're having a drug interaction

You may be experiencing an interaction between ashwagandha and ramipril if:

• You feel dizzy or lightheaded, especially when standing up.

• You experience low blood pressure symptoms, such as faintness or weakness.

• You notice headaches or fatigue.

• You have changes in heart rate, such as palpitations.

• You develop digestive symptoms, including nausea or stomach upset.

• Symptoms start after starting ashwagandha or increasing the dose while taking ramipril.

What you should do

If you have any of the above symptoms, you should:

• Speak to your GP or pharmacist for advice as soon as possible.

• Do not stop taking ramipril suddenly unless advised by a healthcare professional.

• Avoid starting, stopping, or changing the dose of ashwagandha without medical advice.

• Seek urgent medical help if you faint or have severe dizziness.

• Tell your healthcare professional about all medicines, supplements, and herbal products you are taking.
  

Important precautions

Pregnancy

You must not take ramipril if you are pregnant or planning to become pregnant, as it can cause serious harm or death to an unborn baby.

Low blood pressure (hypotension)

Both ramipril and ashwagandha can lower blood pressure; taking them together may cause your blood pressure to drop too low, leading to dizziness or fainting.

Autoimmune diseases (e.g., lupus, rheumatoid arthritis, multiple sclerosis)

Ashwagandha can increase immune system activity, which may worsen the symptoms of autoimmune conditions.

Food and drink warnings

Alcohol

Drinking alcohol while taking ramipril can cause your blood pressure to drop too low. This may make you feel dizzy, lightheaded, or faint, especially when standing up. It is best to keep alcohol intake to a minimum, especially when you first start the medicine or if your dose is increased.

Salt substitutes (potassium-rich)

Ramipril can increase the levels of potassium in your blood. You should avoid using salt substitutes that contain potassium (such as Lo-Salt) because this can lead to dangerously high potassium levels (hyperkalaemia).

Using other medicines

Taking multiple medicines? Our Medicines Interaction Checker helps you check whether your prescriptions, over-the-counter medicines, and supplements are safe to take together. Simply search for your medicines to see potential interactions and what to do about them.

Disclaimer

This information is for general educational purposes only and should not be relied upon as a substitute for professional medical advice. Always consult your GP, pharmacist, or another qualified healthcare professional before making decisions about your medications. Individual circumstances may vary, and only a healthcare professional who knows your medical history can provide personalised guidance.