Acemetacin capsules for pain and inflammation

About acemetacin

Anti-inflammatory painkillers like acemetacin are also called non-steroidal anti-inflammatory drugs (NSAIDs), or sometimes just 'anti-inflammatories'. Acemetacin is prescribed to ease pain and reduce inflammation in people with painful muscles or joints. Typical conditions it is prescribed for include אוסטיאוארתריטיס, דלקת מפרקים שגרונית ו ankylosing spondylitis. It is also prescribed to ease pain after surgical operations.

Acemetacin works by blocking the effect of natural substances called cyclo-oxygenase (COX) enzymes. These enzymes help to make other chemicals in the body, called prostaglandins. Some prostaglandins are produced at sites of injury or damage, and cause pain and inflammation. By blocking the effect of COX enzymes, fewer prostaglandins are produced, which means pain and inflammation are eased.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking acemetacin, it is important that your doctor knows:

• If you have ever had an allergic reaction to any other NSAID (such as aspirin, naproxen, diclofenac, and indometacin), or to any other medicine.

• If you have ever had a problem with bleeding from the stomach or intestines, such as from a peptic or duodenal ulcer.

• אם יש לך אסתמה או כל הפרעה אלרגית אחרת.

• אם יש לך מצב לבבי, או בעיה בכלי הדם או במחזור הדם.

• אם את בהריון, מנסה להיכנס להריון, או מניקה.

• אם אי פעם היו לך בעיות בקרישת דם.

• If you have an inflammatory bowel disorder such as Crohn's disease or ulcerative colitis.

• אם יש לך הפרעה ברקמת חיבור כמו זאבת מערכתית. זהו מצב דלקתי הנקרא גם זאבת או SLE.

• If you have any of the following conditions: high blood pressure; epilepsy; Parkinsonism; a mental health problem.

• אם יש לך בעיות בתפקוד הכבד שלך, או אם יש לך בעיות בתפקוד הכליות שלך.

• אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about acemetacin, and it will also provide you with a full list of the side-effects which you could experience from taking it.

• Take acemetacin exactly as your doctor tells you to. The usual dose for adults is one 60 mg capsule taken twice daily, preferably morning and evening. If it is necessary, your doctor may increase the dose to one capsule three times daily.

• Take acemetacin with food; during a mealtime is ideal. This will help to protect your stomach from side-effects such as indigestion and stomach irritation.

• Swallow the capsule whole with a drink of water. Do not chew or open the capsules.

• If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case take the next dose when it is due and leave out the forgotten dose). Do not take two doses together to make up for a missed dose.

• Your doctor will try to prescribe you the lowest dose for the shortest time in order to reduce the risk of side-effects. If you need to take acemetacin over a period of time, your doctor may want to prescribe another medicine along with it to protect your stomach from irritation.

• Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress.

• If you have asthma, symptoms such as wheeze or breathlessness can be made worse by anti-inflammatories such as acemetacin. If this happens to you, you should stop taking the capsules and see your doctor as soon as possible.

• There is known to be a small increased risk of heart and blood vessel problems in people taking some anti-inflammatory painkillers long-term. Your doctor will explain this to you and will prescribe the lowest suitable dose for the shortest time in order to reduce the risk. Do not take more than the recommended dose.

• If you buy any medicines, check with a pharmacist that they are safe to take with an anti-inflammatory like acemetacin. This is because you should not take these capsules with any other anti-inflammatory painkiller, some of which are available in cold and flu remedies which can be bought 'over the counter'.

• If you are due to have an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with acemetacin. The best place to find a full list of the side-effects which can be associated with your medicine, is from the manufacturer's printed information leaflet supplied with the medicine. Alternatively, you can find an example of a manufacturer's information leaflet in the reference section below. Speak with your doctor or pharmacist if any of the following continue or become troublesome.

חשוב: if you experience any of the following less common but possibly serious symptoms, stop taking acemetacin and contact your doctor for advice straightaway:

• אם יש לך קשיי נשימה כמו צפצופים או קוצר נשימה.

• אם יש לך סימנים כלשהם לתגובה אלרגית כמו נפיחות סביב הפה או הפנים, או פריחה עורית מגרדת חמורה.

• If you pass blood or black stools, bring up blood, or have severe tummy (abdominal) pains.

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהקפסולות, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

• שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

• יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.