Fludrocortisone tablets
נבדק על ידי Sid Dajaniעודכן לאחרונה על ידי Michael Stewart, MRPharmSLast updated 15 Sept 2022
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Fludrocortisone belongs to a class of medicines known as corticosteroids (more commonly called steroids).
You must take fludrocortisone each day.
If you need any medical treatment, make sure the person treating you knows you are taking fludrocortisone tablets.
Your pharmacist will give you a blue 'Steroid Treatment Card' - carry this with you at all times.
At a glance
Fludrocortisone is a corticosteroid medicine, also known as an oral steroid.
It replaces natural corticosteroids in people with Addison's disease or after adrenal gland removal.
This medicine helps regulate blood pressure and blood salt levels.
You will receive a 'Steroid Treatment Card' which you should carry at all times.
If you become ill or think you have been exposed to infections like chickenpox, see your doctor immediately.
Common side-effects include fluid retention, tummy pain, muscle weakness, and mood changes.
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המשך לקרוא למטה
About fludrocortisone
סוג התרופה | Corticosteroid |
שימוש עבור | Replacement treatment in people with Addison's disease or following surgical removal of the adrenal glands |
נקרא גם | Fludrocortisone acetate |
זמין כ | טבליות |
Fludrocortisone belongs to a group of medicines called corticosteroids. It is sometimes referred to simply as an oral steroid. It is used as a replacement treatment for people whose adrenal glands do not produce sufficient natural corticosteroids - a condition known as מחלת אדיסון. It is also used for people who have had surgery to remove their adrenal glands and who therefore no longer produce natural corticosteroids.
The two natural corticosteroids which need replacing are called hydrocortisone (cortisol) and aldosterone. The body's natural hydrocortisone can be replaced by taking hydrocortisone as a tablet or injection, but a substitute medicine has to be used to replace the body's natural aldosterone. Fludrocortisone is the substitute medicine used. It is used because its action in the body is similar to that of aldosterone. It will help to regulate your blood pressure and blood salt level.
Before taking fludrocortisone
חזרה לתוכןSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking fludrocortisone it is important that your doctor or pharmacist knows:
אם את בהריון או מניקה.
אם יש לך לחץ דם גבוה (יתר לחץ דם).
If you have had a heart attack or have any other heart problems.
אם יש לך בעיות בכבד או בכליות.
If you (or anyone in your family) have diabetes or increased eye pressure (glaucoma).
If you have weakened bones (osteoporosis).
If you have an underactive thyroid gland.
If you have ever had a mental health problem - for example, depression.
אם יש לך אפילפסיה.
If you have had a stomach ulcer or an inflammatory bowel disorder.
אם יש לך כל סוג של זיהום, או אם אי פעם היה לך שחפת (TB).
If you (or anyone you are in close contact with) have recently had chickenpox, measles or shingles.
If you have ever had a blood clot in an artery or vein.
If you have a condition known as myasthenia gravis, which causes muscle weakness, or if you have ever developed muscle pain after taking a steroid medicine.
אם אתה נוטל תרופות אחרות, כולל כאלה שניתן לרכוש ללא מרשם, וכן תרופות צמחיות ומשלימות.
אם אי פעם הייתה לך תגובה אלרגית לתרופה.
המשך לקרוא למטה
How to take fludrocortisone
חזרה לתוכןBefore starting this treatment, read the manufacturer's printed information leaflet from inside the pack and be careful to follow any printed instructions you have also been given. The leaflet will give you more information about fludrocortisone and a full list of side-effects which you may experience from taking it.
Your doctor or pharmacist will tell you how many tablets to take. This information will also be on the label of the packet of tablets to remind you. It is important that you take fludrocortisone exactly as your doctor has told you. It is usual to take fludrocortisone once daily, just after breakfast.
Try to take your dose at the same time each day, as this will help you to remember to take it. If you do forget to take a dose, take it as soon as you remember. If you do not remember until the following day, skip the missed dose. Do not take two doses together to make up for a forgotten dose.
Continue to take fludrocortisone tablets regularly each day - it is vital for your well-being. Fludrocortisone replacement treatment is almost always lifelong.
להפיק את המרב מהטיפול שלך
חזרה לתוכןYou will be given a 'Steroid Treatment Card' which says that you are on steroids and contains some important advice for you. It is important that you read this card and carry it with you at all times. It also contains details about your dose, the length of time you have been taking fludrocortisone, and who prescribed it for you. Please make sure that this information is kept up to date.
If you are having an operation or dental treatment or any treatment for an injury, tell the person carrying out the treatment that you are taking fludrocortisone and show them your treatment card.
Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. Your doctor will want you to have tests from time to time to make sure you remain free from some of the unwanted side-effects of treatment.
If you become ill it is important that you make an appointment to see your doctor straightaway. Also, if you come into contact with anyone who has measles, shingles or chickenpox (or anyone who suspects they might have them), you should see your doctor as soon as possible.
Make sure you get your next supply of tablets well in advance so that you never run out. People with Addison's disease are entitled to free NHS prescriptions.
Some vaccines may not be suitable for you. If you need any immunisations, make sure you mention that you are taking fludrocortisone.
If you need to buy any medicines, check with a pharmacist that they are suitable for you to take with your other medicines.
'Thinning' of the bones (osteoporosis) is more common in people with Addison's disease compared to the general population. Regular exercise, a good diet and not smoking will all help to prevent the development of osteoporosis, or reduce its severity.
המשך לקרוא למטה
Can fludrocortisone cause problems?
חזרה לתוכןAlong with their useful effects, all medicines can cause unwanted side-effects although not everyone experiences them. The table below lists some of the more common side-effects associated with fludrocortisone treatment.You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects usually improve as your body adjusts to the new medicine, but other unwanted effects may develop with long-term fludrocortisone treatment. Speak with your doctor or pharmacist if any of the following side-effects continue or become troublesome.
Common fludrocortisone side-effects | מה אני יכול לעשות אם אני חווה את זה? |
Fluid retention causing swollen feet and ankles | Whenever possible, sit with your feet up |
Tummy (abdominal) pain, feeling sick (nausea) or bloated, indigestion | Stick to simple meals and avoid rich or spicy foods |
Muscle weakness or feeling tired | If this happens, do not drive and do not use tools or machines until you feel better |
Mood or behavioural changes, especially at the beginning of treatment | If you become confused, anxious, irritable, have trouble sleeping or start having worrying thoughts about harming yourself, speak with your doctor as soon as possible |
Increased appetite or weight gain, irregular periods in women | אם אחד מאלה הופך לבעייתי, פנה לרופא שלך |
Long-term treatment may cause other unwanted effects | If you have any symptoms which cause you concern, you should arrange to see your doctor for advice |
חשוב: you should let your doctor know if you start to experience blurred vision or other vision problems whilst taking fludrocortisone.
If you experience any other symptoms which you think may be due to this medicine, discuss them with your doctor or pharmacist.
How to store fludrocortisone
חזרה לתוכןשמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.
Some brands of fludrocortisone tablet may need to be stored in a refrigerator (between 2°C and 8°C). Check the manufacturer's information that comes with your medicine.
Keep the container tightly closed.
מידע חשוב על כל התרופות
חזרה לתוכןמידע חשוב על כל התרופות
Never take more than the prescribed dose. If you suspect that someone has taken an overdose of this medicine, go to the accident and emergency department of your local hospital. Take the container with you, even if it is empty.
תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.
אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.
אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.
דווח על תופעות לוואי לתרופה או חיסון
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שאלות נפוצות
What is fludrocortisone and why is it prescribed?
Fludrocortisone is a type of corticosteroid, sometimes called an oral steroid. It's prescribed to replace natural corticosteroids that your adrenal glands aren't producing enough of, as seen in conditions like Addison's disease or after adrenal gland removal surgery. Specifically, it acts like aldosterone, a natural corticosteroid, to help regulate your blood pressure and salt levels.
What should I do if I forget to take my fludrocortisone dose?
If you forget to take a dose, take it as soon as you remember. However, if you don't remember until the following day, you should skip the missed dose. It's important not to take two doses together to make up for a forgotten one.
Are there any specific medical conditions that might make fludrocortisone unsuitable for me?
Yes, there are several conditions your doctor or pharmacist needs to know about before you start fludrocortisone. These include high blood pressure, heart problems, liver or kidney issues, diabetes, glaucoma, weakened bones (osteoporosis), an underactive thyroid, mental health problems, epilepsy, stomach ulcers, inflammatory bowel disorder, any current infection (including tuberculosis), recent exposure to chickenpox, measles or shingles, a history of blood clots, or myasthenia gravis.
Why is it important to carry a 'Steroid Treatment Card'?
It is vital to carry a 'Steroid Treatment Card' at all times because it informs healthcare professionals that you are taking steroids. This card contains important advice for you and details about your dose, how long you've been taking fludrocortisone, and who prescribed it. You should always show this card if you're having an operation, dental treatment, or treatment for an injury.
What should I do if I become unwell or come into contact with someone who has measles, shingles, or chickenpox?
If you become ill, it's important to make an appointment to see your doctor straight away. Similarly, if you come into contact with anyone who has measles, shingles, or chickenpox (or suspects they might have them), you should also see your doctor as soon as possible.
Can fludrocortisone affect my bones?
Yes, 'thinning' of the bones, known as osteoporosis, is more common in people with Addison's disease compared to the general population. To help prevent or reduce the severity of osteoporosis while on treatment, regular exercise, a good diet, and not smoking are recommended.
Is it normal to have mood changes or muscle weakness when taking fludrocortisone?
Mood or behavioural changes, such as confusion, anxiety, irritability, trouble sleeping, or worrying thoughts about self-harm, can occur, especially at the beginning of treatment. Muscle weakness or feeling tired are also possible side-effects. If you experience these, especially if they are severe or concerning, you should speak with your doctor as soon as possible.
Do I need to take fludrocortisone for the rest of my life?
Yes, fludrocortisone replacement treatment is almost always lifelong. It is vital for your well-being that you continue to take these tablets regularly each day as directed by your doctor.
קריאה נוספת והפניות
- Manufacturer's PIL, Fludrocortisone acetate 0.1 mg Tablets; Mylan, The electronic Medicines Compendium. Dated October 2021.
- תרופות מלאות BNF מהדורה 89; האגודה הרפואית הבריטית והחברה המלכותית לפרמקולוגיה של בריטניה הגדולה, לונדון.
המשך לקרוא למטה
About the authorView full bio

מייקל סטיוארט, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

סיד דג'אני
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
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Next review due: 13 Mar 2027
15 Sept 2022 | הגרסה האחרונה

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