גליבוריד לסוכרת
Glynase
נבדק על ידי Sid Dajaniעודכן לאחרונה על ידי מייקל סטיוארט, MRPharmSעודכן לאחרונה 27 בפברואר 2023
עומד בהנחיות העריכה של Patient
- הורדהורד
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- Language
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Take glyburide with, or just after, your first main meal of the day (usually breakfast).
Remember to follow any advice you have been given about your diet and taking exercise.
Common side-effects include stomach upset and low blood sugar (hypoglycemia). Make sure you know how to recognise the symptoms of low blood sugar. These include feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy.
במבט חטוף
Glyburide is a medicine for type 2 diabetes, also known as glibenclamide.
It helps control blood sugar by increasing insulin production from your pancreas.
Take glyburide exactly as your doctor tells you, usually once a day with breakfast.
Possible side-effects include nausea, constipation, diarrhoea, and low blood sugar.
Be aware of the signs of low blood sugar (hypoglycemia) and know how to treat it.
Do not drink alcohol as it can affect your blood sugar control.
הירשמו לקורס הסוכרת החינמי שלנו בן 10 שבועות!
בכל שבוע, נחקור נושא שונה שיעזור לך להבין ולנהל טוב יותר את הסוכרת שלך, כולל חיי היומיום ותרופות, רווחה נפשית, הטכנולוגיה העדכנית ביותר בתחום הסוכרת ותזונה.
על ידי הרשמה אתה מקבל את שלנו מדיניות הפרטיות שלנו. באפשרותך לבטל את המנוי בכל עת. לעולם לא נמכור את הנתונים שלך.
About glyburide
סוג התרופה | A sulfonylurea antidiabetic medicine |
שימוש עבור | Type 2 diabetes mellitus |
נקרא גם | Glynase®; Glucovance® (glyburide with metformin) |
זמין כ | טבליות |
Insulin is a hormone which is made naturally in your body, in the pancreas. It helps to control the levels of sugar (glucose) in your blood. If your body does not make enough insulin, or if it does not use the insulin it makes effectively, this results in the condition called diabetes (diabetes mellitus).
People with סוכרת need treatment to control the amount of sugar in their blood. This is because good control of blood sugar levels reduces the risk of complications later on. Some people can control the sugar in their blood by making changes to the food they eat but, for other people, medicines like glyburide are given alongside the changes in diet.
Glyburide (also know as glibenclamide) works by increasing the amount of insulin that your pancreas produces. This helps to reduce the amount of sugar in your blood.
Glyburide is also available in combination with another antidiabetic medicine called metformin. This combination reduces the number of tablets you need to take each day.
Before taking glyburide
Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking glyburide it is important that your physician knows:
אם את בהריון, מנסה להיכנס להריון או מניקה.
אם יש לך בעיות בתפקוד הכבד שלך, או בתפקוד הכליות שלך.
If you have been told you have porphyria or glucose 6-phosphate dehydrogenase (G6PD) deficiency. These are rare inherited disorders.
אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.
אם אי פעם הייתה לך תגובה אלרגית לתרופה.
How to take glyburide tablets
Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about glyburide tablets and will provide you with a full list of the side-effects which you may experience from taking them.
Take glyburide exactly as your physician tells you to. The usual starting dose is 5 mg daily. It is prescribed as a single dose to be taken with, or immediately after, breakfast.
Depending on your blood sugar (glucose) levels, your daily dose may need to be increased. Your physician will do this slowly, usually increasing by one 2.5 mg tablet each week. Your blood sugar levels will need to be tested regularly.
If you need higher doses your physician may ask you to take glyburide twice each day. If this happens take each dose with a meal or snack and try to space your doses evenly.
Different manufacturers' products may contain different amounts of glyburide and have different recommended doses. Each time you get a prescription make sure you receive the same strength of tablet as before. Ask the pharmacist for advice if you are unsure.
If you forget to take a dose at the usual time, take it with your next meal. If you do not remember until the following day, skip the missed dose. Do not take two doses on the same day to make up for a forgotten dose.
להפיק את המרב מהטיפול שלך
It is important that you keep your regular physician's and laboratory appointments. This is so that your progress can be monitored. You will need regular check-ups with an eye clinic and a foot clinic as well as with your physician and diabetes clinic.
Your physician may recommend that you test for sugar (glucose) in your blood regularly to check that your diabetes is being controlled. Your physician will show you how to do this.
If you have been given advice by your physician about changes to your diet, stopping smoking or taking regular exercise, it is important for you to follow the advice you have been given.
Make sure you know what it feels like if your blood sugar drops too low. This is known as hypoglycemia, or a 'hypo'. The first signs of hypoglycemia are feeling shaky or anxious, sweating, looking pale, feeling hungry, having a feeling that your heart is pounding (palpitations), and feeling dizzy. If this happens, eat something containing sugar, such as dextrose tablets, sugary candy or a sugary soda (non-diet). Then follow this up with a snack such as a sandwich or a banana.
Low blood sugar can occur if you miss a meal, if you exercise more than usual, if you are ill, or if you drink alcohol.
Do not drink alcohol, as it can affect the control of your blood sugar. Ask your physician if you need further advice about this.
If you are a driver you should take special care, as your ability to concentrate may be affected if your diabetes is not well controlled. You may be advised to check your blood sugar levels before you travel and to have a snack with you on long journeys.
All US states have special licensing laws for drivers with medical conditions. You may be required to report your diabetes to local agencies. Ask your physician for advice about the laws in your state.
If you get unusually thirsty, pass urine more frequently than normal, or feel very tired, you should let your physician know. These are signs that there is too much sugar in your blood and your treatment may need adjusting.
Check with your physician before taking up any new physical exercise, as this will have an effect on your blood sugar levels and you may need to check your blood levels more regularly.
If you are due to have an operation or dental treatment, you should tell the person carrying out the treatment that you have diabetes and give them a list of the medicines you are taking.
If you buy any medicines, always check with a pharmacist that they are suitable for you to take.
Treatment for diabetes is usually lifelong. Continue to take the tablets unless you are advised otherwise by your physician.
Can glyburide cause problems?
Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with glyburide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your physician or pharmacist if any of the following continue or become troublesome.
Common glyburide side-effects | מה אני יכול לעשות אם אני חווה את זה? |
בחילה או הקאה | היצמד למאכלים פשוטים - הימנע ממאכלים עשירים או חריפים |
Hard stools that are difficult to pass (constipation) | Eat a well-balanced diet and drink plenty of water |
Loose, watery stools (diarrhea) | שתו הרבה מים כדי להחליף נוזלים שאבדו |
Signs of low blood sugar (hypoglycemia) : feeling shaky or anxious, sweating, looking pale, feeling hungry, feeling that your heart is pounding (palpitations), feeling dizzy | Eat something containing sugar such as a sweet cookie or a sugary drink (not diet) and follow this up with a snack such as a sandwich. Tell your physician if you notice these symptoms |
Increase in weight | If this becomes a problem, let your physician know at your next check-up |
If you experience any other symptoms which you think may be due to this medicine, speak with your physician or pharmacist.
How to store glyburide
שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.
יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.
מידע חשוב על כל התרופות
מידע חשוב על כל התרופות
Never take more than the prescribed dose. If you suspect that you or someone else might have taken an overdose of this medicine, go to the emergency room of your local hospital. Take the container with you, even if it is empty.
תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.
Do not keep out-of-date or unwanted medicines. Ask your pharmacist about ways to dispose of medicines safely in your local area.
אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.
דווח על תופעות לוואי לתרופה או חיסון
אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה אתר כרטיס צהוב.

לא בטוחים לגבי ערבוב תרופות?
בדוק אינטראקציות אפשריות בין תרופות, תוספים ומזונות לפני נטילתם יחד.
שאלות נפוצות
What is the primary difference between glyburide and insulin?
Glyburide works by encouraging your own pancreas to produce more insulin, thereby helping to reduce blood sugar. Insulin, on the other hand, is a hormone made naturally in the body that helps control blood sugar levels directly.
Are there any specific situations where glyburide might not be suitable for me?
Yes, glyburide might not be suitable if you are pregnant, trying to conceive, or breastfeeding. It's also important for your physician to know if you have liver or kidney problems, or if you have rare inherited disorders like porphyria or G6PD deficiency. Always inform your physician about all other medicines you are taking, including non-prescription, herbal, and complementary medicines, and if you've ever had an allergic reaction to any medicine.
Can I take other medications, including over-the-counter ones, while on glyburide?
You should always inform your physician about all other medicines you are taking, including those available without a prescription, as well as herbal and complementary medicines. It's also important to check with a pharmacist before taking any new medicines to ensure they are suitable for you, as some may affect your blood sugar control or interact with glyburide.
What should I do if my blood sugar levels seem consistently high, even with glyburide?
If you experience symptoms like unusual thirst, passing urine more frequently than normal, or feeling very tired, these could be signs that your blood sugar is too high. You should let your physician know, as your treatment may need adjusting.
Is it safe to drive while I'm taking glyburide for diabetes?
If you are a driver, you should take special care, as your ability to concentrate may be affected if your diabetes is not well controlled. You may be advised to check your blood sugar levels before driving and to carry a snack with you on long journeys. You may also be required to report your diabetes to local agencies due to special licensing laws for drivers with medical conditions, so it's best to ask your physician for advice on the laws in your state.
קריאה נוספת והפניות
- FDA Drug Label, Glynase® PresTab (glyburide) tablets; Pharmacia and Upjohn Company LLC. DailyMed, National Institutes of Health, U.S National Library of Medicine. Dated October 2017.
אודות המחברצפה בפרופיל המלא

מייקל סטיוארט, MRPharmS
מנהל סקירת עלוני תרופות – קבלן, רוקח
BPharm (Hons), MRPharmS
מיכאל הוא רוקח קהילתי הפועל במידלנדס ודרום יורקשייר עם יותר מ-20 שנות ניסיון בייעוץ על תרופות ומצבים רפואיים. יש לו רקע חזק בהכשרת בריאות, לאחר שהפיק והעביר קורסי הכשרה לצוותי בתי מרקחת ולעובדי מסגרות טיפול מגורים, כולל אחיות. הוא גם תרם לוועדות ייעוץ רוקחות לניהול מצבים בעלי חומרה נמוכה בקהילה.
אודות המבקר

סיד דג'אני
סולטן דג'אני סיים את לימודיו בבית הספר לרוקחות בלונדון בשנת 1994 והפך לחבר הצעיר ביותר שנבחר למועצת החברה המלכותית לרוקחות מאז היווסדה בשנת 1842.
היסטוריית המאמר
המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.
המאמר זמין גם ב אנגלית, גרמנית, ספרדית, צרפתית, איטלקית, פורטוגזית, הינדי, עברית, ערבית, and שוודית.
Next review due: 26 Aug 2027
27 בפברואר 2023 | הגרסה האחרונה
1 במרץ 2017 | פורסם במקור
נכתב על ידי:
מייקל סטיוארט, MRPharmS

שאלו, שתפו, התחברו.
עיין בדיונים, שאל שאלות ושתף חוויות במאות נושאים בריאותיים.
הירשמו לניוזלטר של פיישנט
המנה השבועית שלך של עצות בריאות ברורות ואמינות - נכתבה כדי לעזור לך להרגיש מעודכן, בטוח ובשליטה.
על ידי הרשמה אתה מקבל את שלנו מדיניות הפרטיות שלנו. באפשרותך לבטל את המנוי בכל עת. לעולם לא נמכור את הנתונים שלך.
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