דלג לתוכן הראשי

Melphalan tablets

Melphalan will be prescribed for you by a specialist doctor.

Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.

If you think you are getting an infection or if you have a high temperature, please contact your doctor straightaway.

At a glance

  • Melphalan is a chemotherapy medicine for certain cancers and conditions that cause rapid cell growth.

  • It works by preventing cells from multiplying, reducing cancer cells or unwanted blood cells.

  • You will need regular blood tests and check-ups during your treatment.

  • Do not get pregnant or father a child during treatment, and use suitable contraception.

  • Avoid immunisations during treatment and for six months after without consulting your doctor.

  • Contact your doctor if you develop a sore throat or a high temperature.

  • Melphalan tablets must be stored in a refrigerator.

המשך לקרוא למטה

About melphalan tablets

סוג התרופה

An alkylating chemotherapy medicine

שימוש עבור

Multiple myeloma; polycythaemia vera

זמין כ

טבליות

Melphalan is used to treat some cancers and conditions where cells in the body rapidly divide and multiply. It is most commonly prescribed for conditions such as מיאלומה נפוצה ו polycythaemia vera. Multiple myeloma is a cancer of the bone marrow. Polycythaemia vera is a bone marrow disease that leads to an abnormal increase in the number of red blood cells in the body. It makes your blood 'thicker' and can make you feel dizzy and short of breath.

In these conditions, certain cells in the body grow and multiply too fast. Melphalan works by preventing cells from multiplying. This reduces the number of cancer cells or unwanted blood cells.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking melphalan it is important that your doctor knows:

  • אם את בהריון או מניקה.

  • If you have any problems with the way your kidneys work.

  • If you have an infection or feel unwell.

  • If you have a rare inherited blood condition called porphyria.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

  • אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

המשך לקרוא למטה

  • Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of tablets. These will give you more information about melphalan and will provide you with a full list of the side-effects which you may experience from taking it.

  • Melphalan will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how to take it. The dose you are prescribed will depend upon the reason why you are taking it, so it is important that you take the tablets exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what the doctor said to you but if you are unsure about how to take the tablets, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.

  • Swallow melphalan tablets whole with a drink of water. Do not break, crush or chew the tablets before you swallow.

  • If you are sick shortly after taking a dose, or if you forget to take a dose at the correct time, contact your doctor or clinic for advice on what to do.

  • You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with melphalan.

  • It is important that you do not get pregnant or father a child while you are taking melphalan. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. If you would like to have children in the future, you should ask your doctor for advice about family planning before you begin taking melphalan. This is particularly important if you are a man, as there is a risk of reduced male fertility or sterility with melphalan treatment.

  • While you are taking melphalan and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking with your specialist doctor first. Melphalan lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

המשך לקרוא למטה

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. While you are taking melphalan you should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment with melphalan, although not everyone experiences these. The table below contains some of the side-effects associated with melphalan. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:

Very common melphalan side-effects (these affect more than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

A high temperature, or symptoms of an infection

Let your doctor know about this straightaway

תחושת חולי (בחילה) או להיות חולה (הקאה)

Stick to simple foods. Let your doctor know about this, as you can be given an anti-sickness medicine

שלשול

Drink plenty of water to replace lost fluids. If this continues, speak with your doctor

Common melphalan side-effects (these affect fewer than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

כיבים בפה

Brushing your teeth 2-3 times a day with a soft toothbrush and regularly using a mouth rinse may help to prevent this. If mouth ulcers become a problem, speak with your doctor

Raised levels of urea in your blood

Your doctor will check for this

נשירת שיער

This is not permanent but speak with your doctor if you are concerned about it

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהטבליות, אנא פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • Melphalan tablets should be stored in a refrigerator at 2°C to 8°C and kept dry.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה למחלקת תאונות וחירום בבית החולים המקומי שלך. קח את המיכל איתך, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אם אתה עובר ניתוח או טיפול שיניים, אמור לאדם שמבצע את הטיפול אילו תרופות אתה נוטל.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

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לא בטוחים לגבי ערבוב תרופות?

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שאלות נפוצות

What is the purpose of melphalan tablets?

Melphalan is a chemotherapy medicine designed to treat conditions where cells in the body grow and divide too quickly, such as multiple myeloma and polycythaemia vera. It works by stopping these rapidly multiplying cells, which helps reduce the number of cancer cells or unwanted blood cells.

Why is it important to tell my doctor about all the medicines I am taking, including those bought without a prescription?

It's important for your doctor to know about all medicines you are taking, including over-the-counter and herbal remedies. This helps ensure that melphalan is suitable for you and to prevent any potential interactions between different medications.

What should I do if I am sick soon after taking my melphalan dose?

If you are sick shortly after taking a dose of melphalan, or if you forget to take a dose at the correct time, you should contact your doctor or hospital clinic for advice on what to do.

Why do I need regular blood tests during my treatment with melphalan?

Regular blood tests and check-ups are important during your treatment with melphalan so your doctor can monitor your progress and ensure the treatment is working effectively and safely.

How can melphalan affect my immune system or resistance to infections?

Melphalan can lower the number of white cells in your blood, which makes your body less resistant to infections. You should avoid being around people who are ill, and contact your doctor immediately if you develop a sore throat or a high temperature.

What should I do if I notice hair loss while taking melphalan?

Hair loss is a possible side-effect of melphalan, but it is not permanent. If you are concerned about hair loss, you should speak with your doctor.

How should I store melphalan tablets at home?

Melphalan tablets should be stored in a refrigerator at a temperature between 2°C and 8°C and kept dry. It is also important to keep all medicines out of the reach and sight of children.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

מייקל סטיוארט, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • Next review due: 21 Aug 2027
  • 17 Aug 2024 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
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