דביגטרן

About dabigatran

Sometimes, harmful blood clots can form in your veins and cause a blockage. This is more likely to happen if you are having certain types of surgery, or if you have a fast irregular heartbeat. Dabigatran works by preventing your blood from clotting as quickly or as effectively as normal. It does this by interfering with a substance in your blood which is involved in the development of blood clots, called thrombin. This means that it can be used to treat unwanted blood clots that have developed in your legs or lungs. It can also be given to prevent blood clots from forming in, for example, your legs, lungs, brain or heart.

You may have been prescribed dabigatran to treat a blood clot causing פקקת ורידים עמוקים או תסחיף ריאתי. Alternatively, you may have been prescribed it to help protect against blood clots if you are having hip or knee surgery, or if you have a certain type of irregular fast heartbeat known as פרפור פרוזדורים.

For many years, a medicine called וורפרין has been commonly used to treat blood clots like these and also to help protect against them. However, people who take warfarin need to have regular blood tests to measure how quickly their blood clots. This often means that the dose of warfarin can change quite frequently. Dabigatran works in a slightly different way to warfarin, so people who take dabigatran do not need to have regular blood tests (although occasional blood tests may still be needed).

Before taking dabigatran

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking dabigatran it is important that your doctor knows:

• אם את בהריון, מנסה להיכנס להריון או מניקה.

• If your kidneys do not work well or if you have problems with the way your liver works.

• If you have any medical problems that may increase your risk of bleeding, or if you are currently bleeding.

• If you have been told you have a condition called antiphospholipid syndrome.

• If you are taking any other prescribed medicines. You must also tell your doctor if you are taking any medicines which are available to buy without a prescription, as well as herbal and complementary medicines.

• אם אי פעם הייתה לך תגובה אלרגית לתרופה.

How to take dabigatran

• Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about dabigatran and will provide you with a full list of the side-effects which you may experience from taking it.

• Take dabigatran exactly as your doctor tells you to. Your doctor or pharmacist will tell you how many capsules to take each day, and how often to take them. Your dose could be one or two capsules, taken once or twice a day. Your dosage information will be printed on the label of the pack to remind you.

• Try to take dabigatran at the same time(s) each day, as this will help you to remember to take your doses regularly.

• Swallow the capsules whole with a drink of water. Do not open the capsule to help you swallow as this will increase the risk that you will experience side-effects such as bleeding. You can take dabigatran either before or after meals.

• Sachets of granules are available for people with swallowing difficulties. The granules should be mixed with apple juice or a soft food like yoghurt. The mixture must be taken within 30 minutes of preparing. Follow the manufacturer's instructions carefully.

• If you forget to take a dose, you can still take it up to six hours before you are due to take your next dose. If it is less than six hours before you need to take your next dose, do not take the missed dose. Miss this dose out completely but remember to take your next dose of dabigatran as normal. Do not take two doses at the same time to make up for the missed dose. If in doubt, speak with your pharmacist or doctor.

• Do not take more doses than your doctor has recommended for you. If this happens by accident, contact your doctor straightaway as you may be at risk of bleeding.

להפיק את המרב מהטיפול שלך

• Try to keep any regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have an occasional blood test if you are taking dabigatran over a period of time.

• If you have had knee surgery, you will be asked to take dabigatran once each day for a total of 10 days. If you have had hip surgery, you will be asked to take dabigatran once each day for 4-5 weeks. If you are taking it for any other reason, you will be asked to take it twice a day for a period of time.

• There are several strengths of dabigatran capsule available. Each time you collect a fresh supply, it is a good idea to check that the strength of the capsules is what you are expecting. If you are at all unsure, your pharmacist will be able to advise you further.

• If you buy any medicines 'over the counter', always check with a pharmacist that they are safe to take with dabigatran. This is because some medicines (such as anti-inflammatory painkillers like aspirin and ibuprofen) can increase the risk of bleeding and should be avoided.

• If you are having any treatment like an operation or dental treatment, tell the person carrying out the treatment which medicines you are taking.

Can dabigatran cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with dabigatran. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

If you experience any other symptoms which you think may be due to dabigatran, speak with your doctor or pharmacist for further advice.

How to store dabigatran

• שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

• יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות