דלג לתוכן הראשי

Cyclopenthiazide tablets

Clinical author's note מייקל סטיוארט 22/04/2019: Navidrex® and Navispare® tablets have been discontinued in the UK. At the time of review there are no branded or generic products containing cyclopenthiazide available in the UK. Cyclopenthiazide may still be available in other countries. This medicine leaflet is based on medical information available in the UK at the time of writing. Please also refer to the manufacturer's information supplied with your medicine.

Cyclopenthiazide is a 'water tablet' (a diuretic).

It is best taken in the morning.

Any side-effects are usually mild, but may include feeling sick or dizzy.

At a glance

  • Cyclopenthiazide is a 'water tablet' (diuretic) used to treat high blood pressure, fluid retention, and heart failure.

  • It works by making your kidneys pass out more urine.

  • Take your dose in the morning to avoid disturbing your sleep.

  • Your doctor may monitor your salt levels with blood tests.

  • Tell your doctor if you experience constant thirst or a dry mouth, as this may indicate dehydration.

  • Seek medical advice before drinking alcohol or taking other medicines with cyclopenthiazide.

המשך לקרוא למטה

About cyclopenthiazide

סוג התרופה

A thiazide diuretic

שימוש עבור

High blood pressure; fluid retention; heart failure

נקרא גם

Navidrex®, Navispare® (discontinued)

זמין כ

טבליות

Cyclopenthiazide belongs to a group of medicines called thiazide diuretics. A diuretic is a medicine which increases the amount of urine that you pass out from your kidneys. They are often referred to as 'water tablets'. Diuretics are a common treatment for לחץ דם גבוה (hypertension). They are also used to clear excess fluid from your body in conditions where your body retains more than it needs. This is called oedema. Cyclopenthiazide is also useful in people who have אי ספיקת לב. Heart failure is a condition where your heart is not functioning as well as it should.

Diuretics like cyclopenthiazide work by interfering with the transport of salt and water across certain cells in your kidneys. The effect of this is to make your kidneys pass out more urine. The removal of fluid reduces your blood pressure and helps reduce the work your heart has to do.

Cyclopenthiazide is usually given alongside other diuretics to treat high blood pressure. When it is used like this, you may be prescribed a combination tablet, such as Navispare®. This brand contains cyclopenthiazide with amiloride. Combination tablets like this help to reduce the number of tablets you need to take each day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking cyclopenthiazide it is important that your doctor knows:

  • אם את בהריון או מניקה.

  • If you have any problems with the way your liver works, or any problems with the way your kidneys work.

  • If you have gout, diabetes or an inflammatory condition called systemic lupus erythematosus (also called lupus, or SLE). These conditions can be made worse by medicines like cyclopenthiazide.

  • If you have been told by a doctor that you have low sodium or potassium levels in your blood, or high calcium levels in your blood.

  • If you have a problem with your adrenal glands, called מחלת אדיסון.

  • אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

המשך לקרוא למטה

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about cyclopenthiazide and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take cyclopenthiazide tablets exactly as your doctor tells you to. The usual dose is ½-1 tablet daily. Your doctor is likely to recommend that you take your dose in the morning. This is so it works during the day and your sleep is not disturbed by you needing to get up to go to the toilet during the night.

  • Swallow the tablet with a drink of water. You can take it either with or without food.

  • If you forget to take a dose, take it as soon as you remember. However, if it is late afternoon when you remember, leave out the forgotten dose and take your next dose as usual on the following day. Do not take two doses on the same day to make up for a missed dose.

  • 'Water tablets' (diuretics) like cyclopenthiazide help you to lose water. Occasionally you may lose too much and become lacking in fluid in the body (dehydrated). Let your doctor know if you feel constantly thirsty, your mouth is dry, or your skin looks and feels dry.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. The salt balance in your bloodstream may be upset by cyclopenthiazide and your doctor may want you to have a blood test from time to time to check for this.

  • If you have been prescribed cyclopenthiazide for high blood pressure (hypertension), your treatment is likely to be long-term. Although many people with high blood pressure do not feel unwell, if left untreated, high blood pressure can harm your heart and damage your blood vessels. This damage may later result in a heart attack, stroke, or kidney problems, so it is important that you continue to take the tablets regularly to help reduce the risk of this. You may also be given some lifestyle and dietary advice by your doctor, such as stopping smoking, reducing the amount of salt in your diet, eating more fruit and vegetables and less saturated fat, and taking some regular exercise. Following this advice will also help to reduce the risk of damage to your heart and blood vessels.

  • Ask your doctor for advice before drinking alcohol while you are on cyclopenthiazide. Alcohol will add to the blood pressure-lowering effect of cyclopenthiazide which will increase the possibility of you experiencing side-effects such as dizziness.

  • If you buy any medicines, check with a pharmacist that they are suitable to take alongside cyclopenthiazide.

  • If you are due to have an operation or any dental treatment, tell the person carrying out the treatment which medicines you are taking.

המשך לקרוא למטה

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with cyclopenthiazide. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common cyclopenthiazide side-effects

מה אני יכול לעשות אם אני חווה את זה?

Feeling sick (nausea), stomach upset

This is usually mild, but it may help to take cyclopenthiazide after food if you are not already doing so

Feeling dizzy, particularly when you stand up (due to low blood pressure)

Getting up more slowly should help. Do not drive and do not use tools or machines while affected

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהטבליות, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה מיד לחדר המיון בבית החולים המקומי שלך. קח איתך את המיכל, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

If you have any questions about this medicine, ask your pharmacist.

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שאלות נפוצות

What is cyclopenthiazide primarily used for?

Cyclopenthiazide is a medicine that helps increase the amount of urine your kidneys pass out. It is commonly used to treat high blood pressure and to clear excess fluid from the body in conditions like oedema or heart failure.

How does cyclopenthiazide work in the body?

This medicine, a 'water tablet', works by affecting how salt and water are transported across cells in your kidneys. This action causes your kidneys to make more urine. This extra fluid removal helps lower your blood pressure and reduces the effort your heart needs to make.

Can I take cyclopenthiazide with other diuretics?

Yes, cyclopenthiazide is often given with other diuretics, especially for high blood pressure. Sometimes, you might be prescribed a combination tablet, which includes cyclopenthiazide and another medicine, to reduce the total number of tablets you need to take each day.

What should I do if I miss a dose of cyclopenthiazide?

If you forget to take a dose, take it as soon as you remember. However, if it's late afternoon when you remember, skip the forgotten dose and take your next dose at the usual time the following day. Never take two doses on the same day to catch up for a missed dose.

What are the common side-effects of cyclopenthiazide and how can I manage them?

Common side-effects include feeling sick (nausea), stomach upset, and dizziness, especially when standing up. For nausea and stomach upset, taking the tablet after food might help. If you feel dizzy, try getting up more slowly. If these issues continue or become bothersome, speak to your doctor or pharmacist.

Why is it important to have regular blood tests while taking cyclopenthiazide?

Cyclopenthiazide can sometimes affect the balance of salts in your bloodstream. Your doctor may ask you to have regular blood tests to check these salt levels and ensure they remain balanced.

Can I drink alcohol while taking cyclopenthiazide?

You should ask your doctor for advice before drinking alcohol. Alcohol can increase the blood pressure-lowering effect of cyclopenthiazide, which could make you more likely to experience side-effects like dizziness.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

מייקל סטיוארט, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • Next review due: 31 Mar 2028
  • 31 Mar 2025 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
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