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נבדק על ידי Sid Dajaniעודכן לאחרונה על ידי מייקל סטיוארט, MRPharmSעודכן לאחרונה 5 אוגוסט 2024

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הוסף למקורות מועדפים בגוגל

Lomustine will be prescribed for you by a specialist doctor. It is usually taken on one day every 6-8 weeks.

Keep your regular appointments with your doctor or hospital. You will need to have frequent blood tests.

If you think you are getting an infection or if you have a high temperature, please contact your doctor straightaway.

About lomustine capsules

סוג התרופה	An alkylating chemotherapy medicine
שימוש עבור	סרטן
נקרא גם	Lomustine 'Medac', CeeNU® (USA)
זמין כ	קפסולות

Lomustine is used to treat some cancers. It is given in particular to treat מחלת הודג'קין when other treatments have not proved effective. It is also prescribed for some brain, lung and skin cancers. Lomustine can be given alongside other medicines or treatments for cancer.

In cancer, certain cells in the body grow and multiply too fast. Chemotherapy medicines like lomustine work by preventing the growth and division of cells. This reduces the number of cancer cells that your body makes.

Before taking lomustine

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking lomustine it is important that your doctor knows:

אם את בהריון או מניקה.
אם יש לך בעיות בתפקוד הכליות שלך.
If you have an infection or feel unwell.
If you have coeliac disease or wheat allergy.
אם יש לך מצב דם נדיר תורשתי שנקרא פורפיריה.
אם אי פעם הייתה לך תגובה אלרגית לתרופה.
אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

How to take lomustine

Before you start this treatment, read any printed information you have been given by your doctor and the printed manufacturer's leaflet from inside your pack of capsules. These will give you more information about lomustine and will provide you with a full list of the side-effects which you may experience from taking it.
Lomustine will be prescribed for you by a specialist doctor who is experienced in treating your condition. Your doctor will calculate what dose is right for you and will tell you how many capsules to take. You will also be told on which day you should take them - it is important that you take lomustine exactly as your doctor tells you to. It is usually taken on just one day every 6-8 weeks (occasionally the dose can be split over three days instead). Your dose will be printed on the label of the pack to remind you about what the doctor said to you but if you are unsure about how to take the capsules, or if you have any other concerns, you should contact your doctor or hospital clinic for advice.
If you are sick (vomiting) shortly after taking a dose, please speak with your doctor or clinic for advice on what to do.

להפיק את המרב מהטיפול שלך

You must try to keep your regular appointments with your doctor or hospital. This is so your doctor can check on your progress. You will need to have regular blood tests and check-ups during your treatment with lomustine.
It is important that you do not get pregnant or father a child while you are taking lomustine. Make sure you have discussed with your doctor which types of contraception are suitable for you and your partner. Women should continue to use contraception for seven months after treatment has finished. Men should not father a child for at least 4 months after finishing treatment. If you would like to have children in the future, you should ask your doctor for advice about family planning before you begin taking lomustine. This is particularly important if you are a man, as there is a risk of reduced male fertility or sterility with lomustine treatment.
While you are taking lomustine and for six months after you have stopped the treatment, do not have any immunisations (vaccinations) without talking to your specialist doctor first. Lomustine lowers your body's resistance and there is a risk that you will get an infection from some vaccines.

Can lomustine cause problems?

Medicines used to treat cancer can have a number of side-effects, some of which can be delayed for several days or weeks after taking the medicine. Most chemotherapy medicines can lower the number of white cells in your blood, which increases the risk of you getting an infection. The risk of this is commonly highest 4-6 weeks after taking lomustine. You should take precautions to reduce the risk of getting an infection - you can do this by avoiding being with people who you know have an infection. If you think you are getting a sore throat or if you have a high temperature, please let your doctor know as soon as possible so that you can get some treatment straightaway.

Your doctor will discuss with you the possibility of unwanted side-effects from your treatment with lomustine, although not everyone experiences these. The table below contains some of the side-effects associated with lomustine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. Please let your doctor know if you experience any of the following:

Lomustine side-effects	מה אני יכול לעשות אם אני חווה את זה?
A high temperature, or symptoms of an infection	Let your doctor know about this straightaway
תחושת חולי (בחילה) או הקאה, אובדן תיאבון	Stick to simple foods - avoid fatty or spicy meals. Let your doctor know about this, as an anti-sickness medicine may help. If you are sick (vomiting) shortly after taking a dose, please speak with your doctor or clinic for advice on what to do
Mouth ulcers, sore mouth	Brushing your teeth 2-3 times a day with a soft toothbrush and regularly using a mouth rinse may help to prevent this. If mouth ulcers become a problem, speak with your doctor
Feeling disorientated, confused or tired; loss of hair (occurs rarely)	If troublesome, let your doctor know
שינויים בכמה בדיקות דם	הרופא שלך יבדוק את אלה

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהקפסולות, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

How to store lomustine

שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.
יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה למחלקת תאונות וחירום בבית החולים המקומי שלך. קח את המיכל איתך, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אם אתה עובר ניתוח או טיפול שיניים, אמור לאדם שמבצע את הטיפול אילו תרופות אתה נוטל.

If you buy any medicines, always check with a pharmacist that they are suitable for you to take with your prescribed medicines.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה אתר כרטיס צהוב.

שאלות נפוצות

What is coeliac disease or porphyria and why do they matter when taking lomustine?

Coeliac disease is a digestive condition where your small intestine becomes inflamed and unable to absorb nutrients, while porphyria is a rare inherited blood condition. It's important for your doctor to know if you have either of these conditions before you start lomustine, as they can affect how the medicine is used and any extra care that might be needed during your treatment.

Why do I need regular blood tests during my lomustine treatment?

Regular blood tests are necessary so your doctor can monitor your progress and check for any changes in your blood count. This is particularly important because lomustine can lower the number of white cells in your blood, increasing your risk of infection, and can also cause other changes to your blood tests.

How should I manage my diet if I experience nausea, vomiting, or loss of appetite?

If you experience nausea, vomiting, or loss of appetite while taking lomustine, it's advised to stick to simple foods and avoid fatty or spicy meals. You should also let your doctor know, as they may be able to prescribe an anti-sickness medicine to help manage these symptoms.

Can lomustine affect my ability to have children in the future?

Yes, lomustine can affect fertility. It is important that women use contraception for seven months after treatment, and men for at least four months after treatment. If you are a man, there is a risk of reduced fertility or sterility with lomustine treatment. If you wish to have children in the future, you should discuss family planning with your doctor before starting treatment.

What should I do if I forget to take my dose or take too much lomustine?

Lomustine should be taken exactly as your doctor tells you. If you are unsure about what to do, or if you suspect you or someone else might have taken an overdose, you should contact your doctor or hospital clinic for advice or go to the accident and emergency department of your local hospital immediately. Remember to take the medicine container with you.

השאלות והתשובות הללו נוצרו מהמידע במאמר זה.