דלג לתוכן הראשי

פליפרידון זריקה ארוכת טווח

Xeplion, Trevicta, Byannli

Paliperidone long-acting injection will be given to you by your doctor or nurse every four weeks to begin with.

If you miss an appointment for an injection, please make another appointment as soon as possible.

The most common side-effects are headache and difficulties sleeping.

במבט חטוף

  • Paliperidone is an antipsychotic medicine given as a long-acting injection.

  • It is used for adults with schizophrenia to help regulate brain chemicals and control symptoms.

  • Injections are given regularly, typically once a month, with 3-monthly and 6-monthly options available.

  • Benefits include not having to remember to take daily tablets.

  • Keep all regular appointments for your injections and monitoring.

  • Tell your doctor if you are pregnant, have a heart condition, or other specified health issues.

  • Do not drink alcohol while on paliperidone as it increases the risk of side-effects.

About paliperidone long-acting injection

סוג התרופה

An antipsychotic medicine

שימוש עבור

Schizophrenia in adults

נקרא גם

Xeplion®; Trevicta®; Byannli®

זמין כ

Long-acting intramuscular depot injection

סכיזופרניה is a mental health condition that causes disordered ideas, beliefs and experiences. You will have been prescribed paliperidone to relieve the symptoms of schizophrenia. Such symptoms include hearing, seeing, or sensing things that are not real, having mistaken beliefs and feeling unusually suspicious. Paliperidone works on the balance of chemical substances in your brain to help control these types of symptoms.

Long-acting or 'depot' injections are used for maintenance once your symptoms have been eased by taking tablets. The injection slowly releases paliperidone into your body. You will need to receive the injection regularly, once every month. A three-monthly injection (Trevicta®) is available for people who are stable on once-monthly injections. There is also a six-monthly injection (Byannli®). The main advantage of a depot injection is that you do not have to remember to take tablets every day.

Before having paliperidone injection

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start having paliperidone injections, it is important that your doctor knows:

  • אם את בהריון או מניקה.

  • If you have a heart condition or blood vessel disease.

  • If you have liver, kidney, or prostate problems.

  • If you have any problems with your breathing.

  • If you have any of the following: epilepsy, דיכאון, מחלת פרקינסון, raised pressure in your eye (glaucoma) or a condition which causes muscle weakness, called מיאסטניה גרביס.

  • If you have ever had yellowing of your skin or the whites of your eyes (צהבת) or a blood disorder.

  • If you are scheduled to have eye cataract surgery.

  • If you have a tumour on your adrenal gland (a condition called phaeochromocytoma), or if you have been told you have 'a prolactin-dependent tumour'.

  • If you have had an allergic reaction to a medicine.

  • אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

How paliperidone long-acting injection is given

  • Before you start the treatment, ask to read the manufacturer's printed information leaflet from inside the pack. It will give you more information about paliperidone and it will also provide you with a full list of the side-effects which you may experience from having it.

  • Paliperidone injection will be given to you by your doctor or nurse. The first two doses will be injected into a muscle in your upper arm. After this, the injections can either be given into a muscle in your arm, or if preferred, the buttocks.

  • If you haven't received paliperidone injection before, you will initially be given a dose of 150 mg and then a dose of 100 mg a week later. From then on, you will need to have one injection each month. Your doctor will adjust the amount of paliperidone given to suit what is right for you.

  • When your dose of once-monthly injection is stabilised, a three-monthly injection is available and may be suitable for you.

להפיק את המרב מהטיפול שלך

  • Your treatment will require careful monitoring to make sure that you get the best possible benefit from paliperidone. Keep your regular doctor's appointments so that you get your injections on time and your progress can be checked. If you miss an appointment for an injection, contact your doctor to arrange for another appointment as soon as possible. This is so that you can be given the injection without any further delay.

  • If you are due to have any dental treatment or an operation, please tell the person carrying out the treatment that you have had a paliperidone injection. This is important because it may interfere with any anaesthetic you receive. If you are having cataract surgery, it is particularly important that you tell your surgeon that you are on paliperidone. This is because an eye problem known as 'floppy iris syndrome' has developed in some people and your doctor will want to advise you about the risks of this.

  • If you buy or take any 'over-the-counter' medicines, check with a pharmacist that they are suitable for you to take with paliperidone.

  • If you have diabetes you may need to check your blood glucose more frequently, as paliperidone may affect the levels of sugar in your blood. Your doctor will advise you about this.

  • If you drink alcohol, please ask your doctor for advice. Alcohol increases the risk of side-effects from paliperidone, so it is best avoided.

Can paliperidone cause problems?

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with paliperidone long-acting injection. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common paliperidone injection side-effects (these affect more than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

Difficulties sleeping

Discuss this with your doctor if it becomes troublesome

כאב ראש

שתו הרבה מים ובקשו מהרוקח שלכם להמליץ על משכך כאבים מתאים. אם הכאבי ראש נמשכים, הודיעו לרופא שלכם

Common paliperidone injection side-effects (these affect fewer than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

Pain at the site of the injection

This should quickly pass. If the area becomes red, swollen or 'lumpy', let your doctor know

תחושת סחרחורת, עייפות או נמנום

אל תנהג ואל תשתמש בכלים או במכונות. אל תשתה אלכוהול

Feeling shaky or restless, unusual or uncontrollable movements

Speak with your doctor

Feeling sick (nausea) or being sick (vomiting), indigestion, tummy (abdominal) discomfort

Stick to simple meals - avoid rich or spicy food

שלשול

שתו הרבה מים כדי להחליף נוזלים שאבדו

עצירות

Drink plenty of water and eat a well-balanced diet

Increased infections, weight increase or loss, mood changes, high blood pressure, toothache, rash, aches and pains

Discuss these with your doctor if any become troublesome

Changes to the results of some medical tests

הרופא שלך יבדוק את אלה

חשוב: if you experience symptoms such as muscle stiffness, a very high temperature (fever), feeling confused, a fast heartbeat and sweating, you should contact your doctor immediately. These can be signs of a rare but serious condition known as neuroleptic malignant syndrome.

כf you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice.

How to store paliperidone

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

מידע חשוב על כל התרופות

If you suspect that you have had an overdose of this medicine, contact your doctor or go to the accident and emergency department of your local hospital.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה אתר כרטיס צהוב.

בודק תסמינים

לא בטוחים לגבי ערבוב תרופות?

בדוק אינטראקציות אפשריות בין תרופות, תוספים ומזונות לפני נטילתם יחד.

שאלות נפוצות

What should I do if I miss an appointment for my paliperidone injection?

It is important to contact your doctor as soon as possible to reschedule your appointment if you miss one. This ensures you receive your injection without further delay, which is crucial for the effectiveness of the treatment.

Are there any specific concerns if I have diabetes and am taking paliperidone?

Yes, if you have diabetes, you might need to check your blood glucose levels more often. Paliperidone can affect your blood sugar, so your doctor will provide specific advice on how to manage this while on the medication.

Can I take other medications, including over-the-counter or herbal remedies, while on paliperidone?

Before taking any other medicines, including those available without a prescription, or any herbal and complementary medicines, you should check with a pharmacist to ensure they are suitable to take with paliperidone. Some medications can interact negatively.

What is 'floppy iris syndrome' and why is it important to tell my surgeon about paliperidone before cataract surgery?

'Floppy iris syndrome' is an eye problem that has been observed in some people taking paliperidone. If you are having cataract surgery, it is particularly important to inform your surgeon about your medication so they can advise you on the potential risks and take necessary precautions during the procedure.

What should I do if I think I'm experiencing Neuroleptic Malignant Syndrome?

If you experience symptoms like muscle stiffness, a very high temperature (fever), confusion, a fast heartbeat, and sweating, you should contact your doctor immediately. These could be signs of a rare but serious condition called neuroleptic malignant syndrome.

קריאה נוספת והפניות

אודות המחברצפה בפרופיל המלא

תמונת מחבר

מייקל סטיוארט, MRPharmS

מנהל סקירת עלוני תרופות – קבלן, רוקח

BPharm (Hons), MRPharmS

מיכאל הוא רוקח קהילתי הפועל במידלנדס ודרום יורקשייר עם יותר מ-20 שנות ניסיון בייעוץ על תרופות ומצבים רפואיים. יש לו רקע חזק בהכשרת בריאות, לאחר שהפיק והעביר קורסי הכשרה לצוותי בתי מרקחת ולעובדי מסגרות טיפול מגורים, כולל אחיות. הוא גם תרם לוועדות ייעוץ רוקחות לניהול מצבים בעלי חומרה נמוכה בקהילה.

אודות המבקר

תמונת מחבר

סיד דג'אני

סולטן דג'אני סיים את לימודיו בבית הספר לרוקחות בלונדון בשנת 1994 והפך לחבר הצעיר ביותר שנבחר למועצת החברה המלכותית לרוקחות מאז היווסדה בשנת 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • Next review due: 24 Aug 2027
  • 17 Aug 2024 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
בודק זכאות לשפעת

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