דלג לתוכן הראשי

Procyclidine

Kemadrin

Procyclidine is used to relieve unwanted side-effects caused by antipsychotic medicines. It may also be used in the early stages of Parkinson's disease.

It is usually prescribed as a three times daily dose, but you may be advised to take it more or less often than this. Take it exactly as your doctor tells you to.

The most common side-effects are a dry mouth, constipation, blurred vision and difficulties passing urine.

At a glance

  • Procyclidine is a medicine used to treat unwanted movement side-effects from some medicines.

  • It also helps with symptoms of Parkinson's disease, like muscle stiffness and tremor.

  • You should take procyclidine exactly as your doctor tells you to.

  • It is important to tell your doctor about any other medicines you are taking.

  • Common side-effects include dry mouth, constipation, and blurred vision.

  • Do not stop taking procyclidine suddenly without speaking to your doctor first.

המשך לקרוא למטה

About procyclidine

סוג התרופה

An antimuscarinic medicine

שימוש עבור

Unwanted 'extrapyramidal side-effects' caused by some medicines, Parkinson's disease and Parkinsonism

נקרא גם

Kemadrin®

זמין כ

Tablets, oral liquid and injection

Procyclidine is used to relieve unwanted side-effects caused by some antipsychotic medicines. Antipsychotic medicines are prescribed for mental health problems such as schizophrenia. As a side-effect of treatment, antipsychotic medicines can sometimes cause unwanted body movements, some of which may be severe. These movement disorders are often referred to as 'extrapyramidal side-effects' or 'Parkinsonism' and include things like uncontrolled face and body movements, shakiness (tremor), and restlessness. Procyclidine is prescribed to relieve these types of symptoms.

Procyclidine is also used to relieve some of the symptoms of מחלת פרקינסון, which include movement problems such as stiff muscles, shakiness (tremor) and eye movements, as well as sweating and producing too much saliva.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking procyclidine it is important that your doctor knows:

  • אם את בהריון, מנסה להיכנס להריון או מניקה.

  • If you have any problems with the way your liver works, or the way your kidneys work.

  • If you have any problems with your heart or blood vessels.

  • If you have prostate problems, or if you have been experiencing difficulty passing urine.

  • If you have been constipated for more than a week or if you have been told you have an obstruction in your bowel.

  • If you have a condition which causes raised pressure in your eyes, such as glaucoma.

  • אם יש לך לחץ דם גבוה (יתר לחץ דם).

  • אם יש לך מצב הגורם לחולשת שרירים, הנקרא מיאסטניה גרביס.

  • If you have ever had a mental health problem called psychosis.

  • אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

המשך לקרוא למטה

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The manufacturer's leaflet will give you more information about procyclidine and a full list of the side-effects which you may experience from taking it.

  • Take procyclidine exactly as your doctor tells you to. When starting your treatment your doctor will give you a small dose (usually half a tablet or 5 ml liquid medicine three times daily), and then may gradually increase your dose.

  • Carefully follow the directions your doctor gives to you. Although procyclidine is usually prescribed as a three times daily dose, you may be advised to take it more or less often than this.

  • It is not important whether you take procyclidine before or after food, although some people find taking it with meals helps prevent feelings of sickness (nausea).

  • Try to take your doses of procyclidine at the same times of day, each day. This will help you to remember to take your doses regularly.

  • If you do forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a missed dose.

  • נסה לשמור על הפגישות הקבועות שלך עם הרופא. זה כדי שהרופא יוכל לבדוק את ההתקדמות שלך.

  • If you buy any medicines, check with a pharmacist that they are safe to take with procyclidine. Some antihistamines and some strong painkillers can interfere with procyclidine and increase the risk of side-effects.

  • If you are having an operation or any dental treatment, tell the person carrying out the treatment that you are taking procyclidine.

  • If you have been taking procyclidine for some time, do not stop taking it without speaking with your doctor first. Stopping suddenly can cause problems so your doctor will want to reduce your dose gradually when this is necessary.

המשך לקרוא למטה

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with procyclidine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common procyclidine side-effects - these affect fewer than 1 in 10 people


מה אני יכול לעשות אם אני חווה את זה?

יובש בפה

נסה ללעוס מסטיק ללא סוכר או למצוץ סוכריות ללא סוכר

עצירות

Try to eat a well-balanced diet and drink several glasses of water each day

Blurred vision, feeling dizzy

Do not drive and do not use tools or machines until you feel better

קושי במתן שתן

If this becomes troublesome, let your doctor know

Less common procyclidine side-effects - these affect fewer than 1 in 100 people

מה אני יכול לעשות אם אני חווה את זה?

תחושת חולי (בחילה) או להיות חולה (הקאה)

Stick to simple foods - avoid rich or spicy meals. Try taking procyclidine after meals if you are not already doing so

A fast heartbeat, skin rash, mood changes, and feeling anxious, confused or forgetful

If any of these become troublesome, let your doctor know

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מתרופה זו, פנה לרופא או לרוקח שלך.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה למחלקת תאונות וחירום בבית החולים המקומי שלך. קח את המיכל איתך, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

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שאלות נפוצות

What is the main purpose of procyclidine?

Procyclidine is primarily used to alleviate unwanted movement disorders, known as 'extrapyramidal side-effects' or 'Parkinsonism', which can be caused by certain antipsychotic medicines. It also helps manage symptoms of Parkinson's disease, including stiff muscles, shakiness, eye movements, sweating, and excessive saliva production.

Can procyclidine interact with other medications I might be taking?

Yes, it can. It's important to inform your doctor about all other medicines you are taking, including those bought without a prescription, as well as herbal or complementary medicines. Some antihistamines and strong painkillers, in particular, can interfere with procyclidine and increase the risk of side-effects.

What should I do if I forget to take a dose of procyclidine?

If you miss a dose, take it as soon as you remember. However, if it's almost time for your next scheduled dose, you should skip the missed dose entirely. Do not take a double dose to compensate for the one you forgot.

Is it safe to stop taking procyclidine suddenly?

No, if you have been taking procyclidine for some time, you should not stop taking it suddenly. Stopping the medicine abruptly can cause problems. Always speak with your doctor first, as they will likely want to reduce your dose gradually when it's necessary to discontinue the treatment.

What are some common side-effects of procyclidine and how can I manage them?

Common side-effects include dry mouth, which can be managed by chewing sugar-free gum or sucking sugar-free sweets; and constipation, which may improve by eating a well-balanced diet and drinking plenty of water. If you experience blurred vision or dizziness, you should not drive or operate machinery until you feel better. If difficulty passing urine becomes troublesome, you should inform your doctor.

Does procyclidine affect blood pressure?

If you have high blood pressure, it's important to inform your doctor before starting procyclidine. While the article doesn't state that procyclidine directly causes changes in blood pressure for everyone, it is listed as a condition your doctor needs to be aware of, suggesting it's relevant to your treatment.

Can procyclidine be taken by pregnant or breastfeeding individuals?

If you are pregnant, trying for a baby, or breastfeeding, you should inform your doctor. They need to know this information before you start taking procyclidine, as suitability may depend on your specific circumstances.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

מייקל סטיוארט, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • הסקירה הבאה מתוכננת ל: 23 אוגוסט 2027
  • 24 פברואר 2023 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
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