דלג לתוכן הראשי

Naltrexone tablets

Adepend

Naltrexone will help you to remain free from your dependence on opiate drugs.

It will be prescribed for you by a specialist clinic.

Keep your regular appointments with your doctor. This is so your progress can be checked.

At a glance

  • Naltrexone is a medicine used to help people stay free from opioid or alcohol dependence.

  • It works by blocking opioid receptors, which stops the euphoric feelings from substance use.

  • Do not take naltrexone if you have used an opiate drug in the last 10 days.

  • Tell all healthcare professionals you are taking naltrexone, especially for pain treatment.

  • Take naltrexone exactly as your doctor tells you, usually one tablet (50 mg) daily.

  • Common side-effects include headaches, muscle aches, nausea, and feeling restless.

המשך לקרוא למטה

About naltrexone

סוג התרופה

An opioid antagonist

שימוש עבור

To help prevent relapse in people with previous opioid or alcohol dependence

נקרא גם

Adepend®

זמין כ

טבליות

You will have been prescribed naltrexone if you have been through an opiate or alcohol detoxification regime and you are committed to remaining drug/alcohol-free. Alongside other forms of treatment and abstinence support, taking naltrexone can help you to remain free from your dependence.

Naltrexone acts by blocking opioid receptors in your brain and nervous system. This means that you will no longer experience the euphoria-like effects that you previously experienced from substance use. Knowing this will help to support your decisions to stay drug/alcohol-free.

Your treatment with naltrexone will be started and supervised by an appropriate specialist.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking naltrexone it is important that your doctor knows:

  • If you have taken any opiate drug in the previous 10 days. This includes any cough medicines or painkillers that contain opiates.

  • אם יש לך בעיות בתפקוד הכבד שלך, או אם יש לך בעיות בתפקוד הכליות שלך.

  • אם את בהריון או מניקה.

  • אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

המשך לקרוא למטה

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about naltrexone and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take naltrexone exactly as your doctor tells you to. Your dose will be printed on the label of the pack to remind you about what was said to you.

  • When starting the treatment, your doctor will give you a small dose of 25 mg a day (half a tablet) and then will increase the dose to one 50 mg tablet a day. The usual maintenance dose is 50 mg (one tablet) each day, although your doctor may suggest that you take naltrexone on three days of the week only (such as two tablets on Mondays and Wednesdays and three tablets on Fridays).

  • Try to take your doses at the same time of day each day, as this will help you to remember to take the tablets regularly. Swallow the tablet with a drink of water. It can be taken either before or after a meal.

  • If you forget to take a dose at your usual time, take it when you remember. If you do not remember until the following day, leave out the forgotten dose but make sure that you remember to take that day's dose. Do not take two doses together to make up for a forgotten dose.

  • Keep your regular appointments with your doctor and programme supervisor. This is so that your progress can be checked. Before you are prescribed naltrexone, your doctor is likely to test you to make sure that you are free from opiates. Also, your doctor will want to take a blood sample from you both before and during your treatment with naltrexone to check that your liver is working well.

  • Keep taking the tablets until your doctor tells you otherwise. You may need to continue to take naltrexone for a number of months, although your doctor will review this regularly.

  • If you are having any medical treatment, you must tell the person carrying out the treatment that you are taking naltrexone. This is particularly important to ensure that you get proper pain treatment in case of an emergency.

  • If you buy any medicines 'over the counter', always check with a pharmacist that they are suitable for you to take with naltrexone. Some medicines for cold and flu symptoms contain weak opioids, as do some medicines for diarrhoea - you must not take these.

  • These tablets are for you - do not give them to anyone else, even if their condition appears to be the same as yours. If they are taken by anyone who is dependent on opioids, they could cause serious life-threatening withdrawal symptoms.

המשך לקרוא למטה

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with naltrexone. You will find a full list in the manufacturer's information leaflet supplied with your tablets. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Very common naltrexone side-effects (these affect more than 1 in 10 people)

מה אני יכול לעשות אם אני חווה את זה?

Headaches, muscle aches and pains

Ask your clinic to recommend a suitable painkiller

Feeling nervous or restless, lack of energy, difficulties sleeping

אם אחד מאלה הופך לבעייתי, התייעץ עם הרופא שלך לקבלת עצה

Feeling sick (nausea), tummy (abdominal) discomfort

Stick to simple meals - avoid rich and spicy food

Common naltrexone side-effects (these affect fewer than 1 in 10 people)

שלשול

Drink plenty of water to replace the lost fluids

עצירות

Try to eat a well-balanced diet and drink plenty of water each day

תחושת סחרחורת

אם זה קורה, אל תנהג ואל תשתמש בכלים או במכונות

Feeling thirsty, feeling shivery, lack of appetite, watery eyes, skin rash, erectile difficulties, difficulties passing urine, and mood changes

אם אחד מאלה הופך לבעייתי, התייעץ עם הרופא שלך לקבלת עצה

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהטבליות, אנא פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה למחלקת תאונות וחירום בבית החולים המקומי שלך. קח את המיכל איתך, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

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שאלות נפוצות

What is the main purpose of taking naltrexone?

Naltrexone is prescribed to help prevent relapse in individuals who have completed an opiate or alcohol detoxification programme and are committed to staying drug/alcohol-free. It works by blocking opioid receptors in the brain, which means you won't experience the euphoric effects from substance use.

How soon after taking opiates can I start naltrexone?

It is important that you have not taken any opiate drug in the previous 10 days before starting naltrexone. This includes any medicines containing opiates, such as some cough medicines or painkillers.

What should I do if I forget to take a dose of naltrexone?

If you forget to take your dose at the usual time, take it as soon as you remember. However, if you don't remember until the following day, you should skip the missed dose and just take that day's dose as usual. Do not take two doses at once to make up for a forgotten dose.

Can I take naltrexone with other medicines, including over-the-counter ones?

You should inform your doctor about all medicines you are taking, including those bought without a prescription, and herbal or complementary medicines, before starting naltrexone. Also, if you buy any over-the-counter medicines, especially for cold, flu or diarrhoea, you must check with a pharmacist to ensure they are suitable to take with naltrexone, as some contain weak opioids and are not safe to take.

How long will I need to take naltrexone?

You should continue taking naltrexone for as long as your doctor advises. You may need to take it for several months, and your doctor will regularly review your treatment plan.

What should I do if I need pain treatment for an emergency while taking naltrexone?

It is very important to tell any medical professional treating you that you are taking naltrexone. This is crucial to ensure you receive appropriate and effective pain treatment, especially in an emergency situation.

What are the common side effects of naltrexone and how can I manage them?

Common side effects include headaches, muscle aches and pains, feeling nervous or restless, lack of energy, difficulties sleeping, feeling sick, and tummy discomfort. For headaches and muscle pain, ask your clinic for a suitable painkiller. If you feel sick or have tummy discomfort, try eating simple meals and avoid rich and spicy food. For other troublesome side effects like nervousness, restlessness, or sleeping difficulties, speak with your doctor for advice.

Why is it important not to give my naltrexone tablets to anyone else?

Naltrexone tablets are specifically prescribed for you. Giving them to someone else, especially if they are dependent on opioids, could cause severe and life-threatening withdrawal symptoms because of the way the medicine works by blocking opioid receptors.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

מייקל סטיוארט, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • Next review due: 23 Jun 2027
  • 16 יוני 2024 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
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