דלג לתוכן הראשי

Pancreatin

Creon, Nutrizym, Pancrex

Pancreatin will help you to digest fat, starch and protein from your diet.

Take pancreatin with every meal or snack.

Drink plenty of water.

At a glance

  • Pancreatin is a medicine that replaces enzymes your pancreas normally makes to help digest food.

  • It is used for conditions like cystic fibrosis or problems with your pancreas.

  • You must take pancreatin every time you eat a meal or a snack.

  • Take your dose immediately before, at the same time as, or immediately after eating.

  • Common side effects include feeling sick, diarrhoea, or tummy pain.

  • If side effects are troublesome or new pain develops, speak to your doctor.

המשך לקרוא למטה

About pancreatin

סוג התרופה

Pancreatic enzyme

שימוש עבור

סיסטיק פיברוזיס
After surgery on the pancreas or stomach
Problems such as pancreatitis or pancreatic cancer

נקרא גם

Creon®, Nutrizym®, Pancrex®

זמין כ

Tablets, capsules, granules and powder

The pancreas normally makes digestive juices which contain chemicals (enzymes). These enzymes are greatly reduced in people with cystic fibrosis, or pancreatic problems, or those who have had their pancreas removed. This can result in food not being digested or absorbed properly - in particular, fatty foods and fat-soluble vitamins (vitamins A, D, E and K).

Pancreatin replaces the enzymes which normally come from the pancreas, and will help your body digest fats, starch and protein. You need to take it every time you eat, which can mean taking many doses each day.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking pancreatin it is important that your doctor or pharmacist knows:

  • If you are allergic to pork protein.

  • If you are pregnant or breastfeeding (although pancreatin is not known to be harmful).

  • אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

המשך לקרוא למטה

  • Before you start this treatment, read the manufacturer's printed information leaflet from inside your pack. The leaflet will give you more information about the specific brand of pancreatin you have been given, and a full list of side-effects which you may experience from taking it.

  • Take pancreatin exactly as your doctor tells you to. Your doctor will tell you how much to take, and may adjust your dose from time to time to make sure it continues to be the right dose for you.

  • You will need to take pancreatin every time you eat a meal or a snack. It is also important that you have plenty to drink with pancreatin.

  • Take your doses either immediately before, or at the same time as, or immediately after, eating your food. This is because acid in your stomach can stop pancreatin from working. The food you are eating will help protect the enzymes from the acid.

  • Pancreatin is available in a variety of different strengths and formulations. Carefully follow the directions for how to take the preparation you have been given.

  • Some preparations can be mixed with food; others need to be swallowed whole and must not be chewed.

  • Some capsules and granules are specially coated to protect them from stomach acid - these need to be taken with slightly acidic fruit juices such as apple or orange.

  • Do not mix pancreatin with very hot food or liquids. Heat will stop pancreatin from working properly.

  • Do not store mixtures of pancreatin; take your dose as soon as possible after mixing with food or drink.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. If you have cystic fibrosis, there will be many aspects to your treatment and you may need to go to a number of different clinics.

  • Children with cystic fibrosis need a high fat and carbohydrate diet. Your doctor will ask a dietician to give you detailed advice. High-energy drink supplements and vitamin supplements may also be needed.

  • Treatment with pancreatin is usually long-term. Continue to take it unless you are advised otherwise.

  • Each time you collect a prescription, check to make sure you have been given the same brand as before. If you are unsure, ask your pharmacist to check for you.

המשך לקרוא למטה

לצד ההשפעות המועילות שלהן, רוב התרופות יכולות לגרום לתופעות לוואי לא רצויות, אם כי לא כולם חווים אותן. תופעות אלו בדרך כלל משתפרות כאשר הגוף שלך מתרגל לתרופה החדשה, אך יש לפנות לרופא או לרוקח אם אחת מתופעות הלוואי הבאות נמשכת או הופכת למטרידה.

Common pancreatin side-effects - these affect fewer than 1 in 10 people who take this medicine

מה אני יכול לעשות אם אני חווה את זה?

Feeling sick (nausea) or being sick (vomiting), loose stools (diarrhoea), tummy (abdominal) pain

Discuss this with your doctor, as the dose you are taking may need adjusting. Let your doctor know straightaway if, after taking pancreatin for some time, you develop any new or severe pain or sickness

עצירות

Remember to drink plenty of water/fluids

Mouth irritation

Swallow pancreatin quickly so that it doesn't stay in your mouth for long. Let your doctor know about this

Sore or itchy bottom (often when taking high doses)

יידע את הרופא שלך על כך

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מתרופה זו, פנה לרופא או לרוקח שלך.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

  • Please check the manufacturer's information leaflet that comes with your medicine for any special storage instructions.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה מיד לחדר המיון בבית החולים המקומי שלך. קח איתך את המיכל, אפילו אם הוא ריק.

אם אתה עובר ניתוח או טיפול שיניים כלשהו, אמור לאדם שמבצע את הטיפול אילו תרופות אתה נוטל.

אם אתה קונה תרופות כלשהן, בדוק עם רוקח שהן מתאימות לשימוש עם התרופות האחרות שלך.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

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שאלות נפוצות

Why do some people need to take pancreatin?

Pancreatin is needed by people whose bodies don't produce enough digestive enzymes. This can happen if you have conditions like cystic fibrosis, pancreatic problems, or if you've had surgery on your pancreas or stomach. Without these enzymes, your body struggles to properly digest and absorb food, especially fats and fat-soluble vitamins.

What is the best way to take my pancreatin dose if I prefer not to swallow tablets whole?

Pancreatin comes in various forms, including capsules, granules, and powder. Some types can be mixed with food, but others must be swallowed whole and should not be chewed. Certain coated capsules or granules need to be taken with slightly acidic fruit juices like apple or orange to work effectively. It's important to follow the specific directions for the type of pancreatin you have been given.

Can I mix pancreatin with hot drinks or food?

No, you should not mix pancreatin with very hot food or liquids. Heat can stop the enzymes in pancreatin from working properly, making the medicine ineffective. Always ensure the food or drink you mix it with is not hot.

What should I do if I notice mouth irritation from taking pancreatin?

If you experience mouth irritation, try to swallow your pancreatin dose quickly to minimise the time it stays in your mouth. If this side-effect continues or becomes troublesome, you should let your doctor know.

How often do I need to take pancreatin?

You need to take pancreatin every time you eat a meal or a snack. This means you will likely take many doses throughout the day to help your body digest food properly. Your doctor will provide specific instructions on your dosage frequency.

Is it important to drink fluids when taking pancreatin?

Yes, it is important to have plenty to drink with pancreatin. This helps with the delivery of the medicine effectively.

What should I do if my usual brand of pancreatin is not available when I get a prescription filled?

Each time you collect a prescription, it's a good idea to check that you have been given the same brand of pancreatin as before. If you are unsure, ask your pharmacist to check for you. Consistency in brand can be important for some medications.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

מייקל סטיוארט, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • Next review due: 4 Mar 2028
  • 4 Mar 2025 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
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