דלג לתוכן הראשי

Phenobarbital for epilepsy

You need to take phenobarbital regularly every day. Take your dose at bedtime.

Phenobarbital may cause you to feel drowsy and unsteady. This often settles down as your body adjusts to the new medicine.

Do not drink alcohol.

At a glance

  • Phenobarbital is an anti-epileptic medicine used to prevent seizures.

  • It is usually taken once a day, at bedtime.

  • Take phenobarbital regularly and do not stop taking it suddenly.

  • It can make you feel sleepy, so avoid alcohol and be careful with driving.

  • Discuss pregnancy plans with your doctor, as it can harm an unborn baby.

  • Tell your doctor if you experience mood changes or distressing thoughts.

  • See your doctor immediately if you have a fever, severe rash, or yellow skin/eyes.

המשך לקרוא למטה

About phenobarbital

סוג התרופה

An anti-epileptic medicine

שימוש עבור

אפילפסיה

זמין כ

Tablets, oral liquid and injection

If you have אפילפסיה, it means that you have had more than one unexplained fit, or seizure. A seizure is a short episode of symptoms caused by a burst of abnormal electrical activity in your brain. Different parts of the brain control different functions of your body, so the symptoms that occur during a seizure will depend on where the abnormal burst of electrical activity occurs. Symptoms that may occur during a seizure can affect your muscles, sensations, behaviour, emotions, consciousness, or a combination of these. The seizures can be prevented in most people by suitable anti-epileptic medication.

Phenobarbital works by stabilising the electrical activity of your brain, which helps to prevent the seizures from occurring.

Some medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking phenobarbital it is important that your doctor knows:

  • אם את בהריון, מנסה להיכנס להריון או מניקה.

  • If you have breathing problems.

  • If you have ever had problems with drug or alcohol dependence.

  • If you have any problems with the way your kidneys work, or with the way your liver works.

  • אם יש לך הפרעת דם תורשתית נדירה הנקראת פורפיריה.

  • אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.

  • אם אי פעם הייתה לך תגובה אלרגית לתרופה.

המשך לקרוא למטה

  • Before you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about phenobarbital and will provide you with a full list of the side-effects which you may experience from taking it.

  • Take phenobarbital exactly as your doctor tells you to. It is usual to take one dose a day, at bedtime. Your doctor will tell you how many tablets to take for the dose. This information will also be printed on the label of the pack to remind you about what the doctor said to you. You need to take phenobarbital regularly every day to prevent the fits (seizures) from occurring.

  • Try to take your doses of phenobarbital at the same time each evening. Having a routine like this will help you to remember to take your doses regularly. Swallow the phenobarbital tablets with a drink of water. You can take them either with or without food.

  • If you forget to take a dose, take it as soon as you remember unless it is nearly time for your next dose, in which case leave out the missed dose. Do not take two doses together to make up for a forgotten dose.

  • Try to keep your regular appointments with your doctor. This is so your doctor can check on your progress. You may need to have blood tests from time to time.

  • When you first start a new treatment for epilepsy there may be a change in the number or type of fits (seizures) you experience. Your doctor will advise you about this.

  • Phenobarbital made by different manufacturers can act in a slightly different way in your body. Because of this, it is recommended that you continue to take tablets/medicine from the same manufacturer as you have had before. So, each time you collect a prescription, check to make sure your supply looks the same. If you are unsure, or if have any questions about your prescription, please ask your pharmacist to check it for you.

  • While you are being treated for epilepsy there is a small risk that you may develop mood changes, distressing thoughts and feelings about suicide. If this happens, you must tell your doctor about it straightaway.

  • People with epilepsy must stop driving at first. Your doctor will advise you about when it may be possible for you to resume driving again. This will usually be after a year free of seizures.

  • Do not stop taking this medicine unless your doctor tells you to do so. Stopping it suddenly can cause your seizures to return and your doctor will want you to reduce your dose gradually if this becomes necessary. Also, taking phenobarbital over a time can lead to your body becoming dependent on it and this is another reason why your doctor will want to reduce your dose slowly.

  • You are advised not to drink alcohol while you are taking phenobarbital. Phenobarbital will make you feel sleepy and drinking alcohol will increase this. Some liquid medicines may contain noticeable amounts of alcohol, read the manufacturer's leaflet for more information.

  • If you are due to have an operation or any dental treatment, please tell the person carrying out the treatment that you are taking phenobarbital.

  • If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside phenobarbital.

  • You should avoid becoming pregnant while you are taking phenobarbital because it could cause harm to your unborn baby.

  • If you are a woman using hormonal contraception ('the pill' or the 'mini pill'), discuss this with your doctor, as phenobarbital interferes with these and could mean you are more likely to become pregnant. Other methods of contraception will be more suitable for you.

  • If you want to have a family, make sure you discuss this with your doctor well in advance of becoming pregnant. This is so that you can be given advice from a specialist before you become pregnant. If you become pregnant while you are taking phenobarbital, you should tell your doctor straightaway.

המשך לקרוא למטה

Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the most common ones associated with phenobarbital. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.

Common phenobarbital side-effects

מה אני יכול לעשות אם אני חווה את זה?

Feeling unsteady

Getting up or moving more slowly should help. If this continues, let your doctor know

Feeling sleepy or tired

Make sure your reactions are normal before you use tools or machines

Feeling short of breath, behavioural changes, mood changes (such as feeling irritable, confused, excited or depressed), impaired memory

אם אחד מאלה הופך לבעייתי, פנה לרופא שלך

חשוב: your doctor will have discussed with you the possibility of some less common but more serious side-effects. Let your doctor know straightaway if you experience any of the following:

  • A high temperature (fever) and swollen glands.

  • A severe skin rash.

  • Yellowing of your skin or the whites of your eyes (jaundice).

אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהתרופה, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.

  • שמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.

  • יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.

  • Liquid medicines should be used within 28 days of opening, unless otherwise stated on the bottle.

מידע חשוב על כל התרופות

לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה מיד לחדר המיון בבית החולים המקומי שלך. קח איתך את המיכל, אפילו אם הוא ריק.

תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.

אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.

אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.

דווח על תופעות לוואי לתרופה או חיסון

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שאלות נפוצות

What should I do if I accidentally miss a dose of phenobarbital?

If you forget to take a dose, take it as soon as you remember. However, if it's almost time for your next dose, you should skip the missed dose and continue with your regular schedule. Do not take two doses together to make up for a forgotten dose.

Can I drink alcohol while taking phenobarbital?

It is advised not to drink alcohol while taking phenobarbital. Phenobarbital can make you feel sleepy, and alcohol will increase this effect. Also, some liquid forms of the medicine might contain alcohol, so it's best to check the manufacturer's leaflet.

How long will I need to take phenobarbital for?

The article does not specify how long you will need to take phenobarbital. It states that you should not stop taking the medicine unless your doctor tells you to do so, as stopping suddenly can cause seizures to return. If stopping is necessary, your doctor will advise you to reduce your dose gradually.

Is it important to take phenobarbital from the same brand each time?

Yes, it is recommended to continue taking tablets or liquid from the same manufacturer. Phenobarbital made by different manufacturers can act slightly differently in your body. Always check your supply each time you get a prescription, and if you are unsure, ask your pharmacist.

What should I do if I notice changes in my mood or thoughts while on phenobarbital?

If you experience mood changes, distressing thoughts, or feelings about suicide, you must tell your doctor about it straightaway. There is a small risk of these happening during treatment for epilepsy.

Are there any medicines I should avoid taking with phenobarbital?

You should tell your doctor about all other medicines you are taking, including those bought without a prescription, and herbal or complementary medicines. Also, if you use hormonal contraception, discuss this with your doctor as phenobarbital can interfere with it.

קריאה נוספת והפניות

המשך לקרוא למטה

About the authorView full bio

Author image

מייקל סטיוארט, MRPharmS

Medicine Leaflet Review Manager – Contractor, Pharmacist

BPharm (Hons), MRPharmS

Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.

About the reviewer

Author image

סיד דג'אני

Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.

היסטוריית המאמר

המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.

  • Next review due: 5 May 2028
  • 5 May 2025 | הגרסה האחרונה

    עודכן לאחרונה על ידי

    מייקל סטיוארט, MRPharmS

    נבדק על ידי

    סיד דג'אני
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