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נבדק על ידי Dr Colin Tidy, MRCGPעודכן לאחרונה על ידי ד"ר טוני הייזל, MRCGPעודכן לאחרונה 26 מרץ 2023
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Many people use indigestion medicines, usually just occasionally but sometimes more regularly. The same medicines can be used to treat more serious medical conditions such as stomach ulcers or acid reflux. If you need to use indigestion medicines regularly it's very important to see a doctor to get it checked out in case it is caused by an underlying condition that needs further investigations and treatment.
במבט חטוף
Indigestion medicines relieve symptoms like discomfort in your upper tummy or chest.
There are three main types: antacids, H2 blockers, and proton pump inhibitors.
They work by reducing stomach acidity or neutralising acid.
Side effects can vary, including diarrhoea, constipation, or headache.
Lifestyle changes like weight loss or avoiding trigger foods can also help.
See a doctor for persistent symptoms or if you are over 55 with frequent indigestion.
Seek medical help for difficulty swallowing, unexplained weight loss, or blood in vomit or stool.

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What is indigestion?
Dyspepsia (indigestion) is used to describe pain and sometimes other symptoms which come from your upper gut (the stomach, oesophagus or duodenum). The symptoms of indigestion often occur soon after eating.
Most people have indigestion from time to time but it doesn't last long and doesn't cause any problems. Some people can have frequent or severe bouts of indigestion and if that is the case, it's very important to see a doctor to get it checked out and receive the right treatment. See also the separate leaflet called Indigestion (Dyspepsia).
When acid from the stomach leaks up into the gullet (oesophagus), the condition is known as acid reflux. This may cause heartburn and other symptoms. See also the separate leaflet called Acid Reflux and Oesophagitis.
What are indigestion medicines?
Indigestion medicines can be used to relieve the symptoms of indigestion such as discomfort in your upper tummy (abdomen) or chest. There are three main types of medicine for indigestion: (see the links for more information about each type of indigestion medicine). These are:
נוגדי חומצה
Antacids usually contain either aluminium או magnesium compounds. They work by reducing the acidity in your stomach. They are often combined with other substances such as alginates, which form a protective layer that floats on the surface of your stomach contents. This helps prevent acid going back up into your gullet (oesophagus) - the tube that connects your mouth to your stomach - and so protects against acid reflux and oesophagitis.
חוסמי H2
These medicines work by reducing the amount of acid made in your stomach. By reducing the acidity in your stomach they can be used to treat indigestion, acid reflux, stomach (gastric) ulcers ו duodenal ulcers.
The most commonly used H2 blocker in the UK was ranitidine but it has been discontinued as a precaution because of some impurities found in the medicine. If your doctor feels that you need an H2 blocker, they may prescribe a different one.
Proton pump inhibitors (PPIs)
These medicines also reduce the amount of acid made in your stomach. They are also used to treat indigestion and acid reflux, and stomach and duodenal ulcers. Proton pump inhibitors are very effective at reducing stomach acid and are particularly effective at treating acid reflux and gastro-oesophageal reflux disease (GORD).
How do indigestion medicines work?
The exact mechanism of action varies between the different types of medication. Proton pump inhibitors stop an enzyme from working so that stomach cells can't pump acid into the stomach. H2 blockers bind to receptors in the stomach cells which interferes with the production of stomach acid. Antacids neutralise the acid in your stomach by stopping the action of an enzyme which creates acid.
What side-effects can indigestion medicines cause?
Indigestion medicines are usually effective and don't cause any side-effects. The following describes some of the more common side-effects but always read the information provided with the medicine. If you have any doubts or concerns then get advice from your pharmacist, nurse or doctor.
נוגדי חומצה
Antacids that contain magnesium tend to act as a laxative and may cause diarrhoea. Antacids that contain aluminium have the opposite effect and may cause constipation.
Many antacids contain both aluminium and magnesium compounds so that there is a neutral effect on your bowels. Antacids that contain magnesium carbonate may release carbon dioxide gas in your gut (bowel) and this can cause belching.
חוסמי H2
The most common side-effects of H2 blockers can include:
מעכבי משאבות פרוטונים
The most common side-effects of proton pump inhibitors include:
Stomach upset - for example, feeling sick (nausea), stomach ache, or wind (flatulence); tummy pain, and being sick (vomiting).
שלשול.
עצירות.
כאב ראש.
If you take a proton pump inhibitor for a long time, you are likely to get rebound symptoms of acid reflux when you stop, because your stomach has got used to making more acid as a response to the medicines. This usually only lasts for a few days, up to a few weeks as a maximum and it can be treated with antacids or H2 blockers.
How to help indigestion without medicine
Apart from taking an indigestion medicine, there are many things you can do to help, such as:
Don't smoke.
Reduce or stop drinking alcohol.
Avoid foods that can make indigestion worse, such as fatty foods or spicy foods.
If you have heartburn reflux, it may help if you:
Try to eat smaller meals more frequently rather than larger meals.
Avoid eating for the few hours before you go to bed.
Raise the head of your bed.
מתי כדאי לפנות לרופא?
You should see a doctor if you continue to have indigestion symptoms despite a few weeks of using an indigestion medicine. You should always see a doctor if you have any of the following:
קושי בבליעה (feeling food getting stuck or feeling a lump in your throat).
Losing weight without dieting.
Having a lot of pain in your stomach (abdomen).
Being sick (vomiting), especially if there is any blood in the vomit.
If you’re over 55 and get frequent bouts of indigestion.
Noticing blood in your poo (stools) when you go to the toilet.
הריון
Indigestion and acid reflux are common in pregnancy. It usually helps to reduce the symptoms if you:
Eat smaller meals more often.
Avoid foods and drinks that might make your indigestion worse.
Try not to eat within a few hours of going to bed.
בחירות המטופלים עבור Digestive health medicines

טיפול ותרופות
תרופה לשלשול
Diarrhoea medicines (medicines used to relieve diarrhoea symptoms) reduce the number of times that you need to go to the toilet, when you have acute diarrhoea. The most commonly used medicine is loperamide. You can buy this from your local pharmacy or get it on prescription from your doctor. Most people only need to take these medicines for a few days and they are not needed for every diarrhoeal illness. Children under the age of 12 years should not take diarrhoea medicines unless their doctor has told them to do so.
מאת ד"ר טוני הייזל, MRCGP

טיפול ותרופות
מעכבי משאבות פרוטונים
Proton pump inhibitors reduce the amount of acid made by the stomach. They are commonly used to treat acid reflux and ulcers of the stomach and part of the gut called the duodenum. Most people who take a proton pump inhibitor do not develop any side-effects.
מאת ד"ר פיליפה וינסנט, MRCGP
שאלות נפוצות
Are there specific types of food I should avoid if I have indigestion?
Yes, it can be helpful to avoid certain foods that might worsen indigestion symptoms. These commonly include fatty foods and spicy foods.
What is the meaning of 'Do not take indigestion remedies'?
The phrase 'Do not take indigestion remedies' would typically mean that you should avoid consuming medications designed to relieve indigestion. This might be advised if you have certain medical conditions, are taking other medications that could interact, or if your symptoms require a different approach to treatment, as determined by a healthcare professional.
What can help relieve sickness caused by indigestion?
While the article focuses on indigestion, general measures to relieve sickness (nausea) caused by indigestion might include trying to avoid trigger foods, eating smaller, more frequent meals, and certain indigestion medications like H2 blockers or proton pump inhibitors can reduce stomach acid which may help with associated sickness symptoms.
If I am pregnant, what are the best ways to manage indigestion and acid reflux?
If you are pregnant and experiencing indigestion or acid reflux, it's often helpful to eat smaller meals more frequently. You should also try to avoid foods and drinks that tend to make your indigestion worse and avoid eating during the few hours before you go to bed.
How long do the rebound symptoms of acid reflux last after stopping proton pump inhibitors?
If you experience rebound symptoms of acid reflux after stopping a proton pump inhibitor, they typically last for a few days, and a maximum of a few weeks. These temporary symptoms can often be managed with antacids or H2 blockers.
קריאה נוספת והפניות
- Corsetti M, Fox M; The management of functional dyspepsia in clinical practice: what lessons can be learnt from recent literature? F1000Res. 2017 Sep 28;6:1778. doi: 10.12688/f1000research.12089.1. eCollection 2017.
- Dore MP, Pes GM, Bassotti G, et al; Dyspepsia: When and How to Test for Helicobacter pylori Infection. Gastroenterol Res Pract. 2016;2016:8463614. doi: 10.1155/2016/8463614. Epub 2016 Apr 28.
- Dyspepsia - pregnancy-associated; NICE CKS, יולי 2022 (גישה בבריטניה בלבד)
- Dyspepsia - proven GORD; NICE CKS, July 2023 (UK access only)
- Dyspepsia - proven functional; NICE CKS, December 2022 (UK access only)
אודות המחברצפה בפרופיל המלא

Dr Colin Tidy, MRCGP
רופא כללי, מחבר רפואי
MBBS, MRCGP, MRCP (Paediatrics), DCH
ד"ר קולין טיידי הוא רופא ב-NHS, הממוקם באוקספורדשייר.
אודות המבקרצפה בפרופיל המלא

Dr Colin Tidy, MRCGP
רופא כללי, מחבר רפואי
MBBS, MRCGP, MRCP (Paediatrics), DCH
ד"ר קולין טיידי הוא רופא ב-NHS, הממוקם באוקספורדשייר.
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Next review due: 24 Mar 2028
26 מרץ 2023 | הגרסה האחרונה
7 Mar 2018 | פורסם במקור
נכתב על ידי:
Dr Colin Tidy, MRCGP

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