Lercanidipine tablets for high blood pressure
Zanidip
נבדק על ידי Sid Dajaniעודכן לאחרונה על ידי Michael Stewart, MRPharmSLast updated 31 Mar 2025
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Take lercanidipine once a day, preferably in the morning. You should take the tablet about 30 minutes before you eat.
Do not drink grapefruit juice whilst you are on lercanidipine. It can interact with the medicine and alter its effect.
When you first start lercanidipine you may get headache, feel flushed, or feel dizzy. These effects are usually mild and only last for a few days.
כf you have any chest pain after taking this medicine, contact your doctor for advice straightaway.
At a glance
Lercanidipine is a medicine for treating high blood pressure.
It works by widening your blood vessels.
Take your tablets with water, around 30 minutes before a meal.
Do not drink grapefruit juice while taking this medicine.
Common side-effects include headache, dizziness, and swollen ankles.
If you get chest pain after taking this medicine, contact a doctor straightaway.
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About lercanidipine
סוג התרופה | A calcium-channel blocker |
שימוש עבור | לחץ דם גבוה |
נקרא גם | Zanidip® |
זמין כ | טבליות |
Lercanidipine is prescribed to treat לחץ דם גבוה (יתר לחץ דם). Although people with high blood pressure often do not feel unwell, if left untreated, high blood pressure can harm the heart and damage blood vessels, and could lead to a heart attack or stroke.
Lercanidipine is known as a calcium-channel blocker because it works by affecting the way calcium passes into certain muscle cells in your blood vessels. The muscle cells need calcium to contract. Lercanidipine reduces the amount of calcium that goes into these muscle cells. This causes the muscle cells to relax, which widens your blood vessels and lowers your blood pressure.
Before taking lercanidipine
חזרה לתוכןSome medicines are not suitable for people with certain conditions, and sometimes a medicine can only be used if extra care is taken. For these reasons, before you start taking lercanidipine it is important that your doctor knows:
אם את בהריון או מניקה.
If you have any problems with the way your liver works, or any problems with the way your kidneys work.
If you have a heart condition, or angina chest pain, or if you have recently had a heart attack.
אם יש לך הפרעת דם תורשתית נדירה הנקראת פורפיריה.
אם אתה נוטל או משתמש בתרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.
אם אי פעם הייתה לך תגובה אלרגית לתרופה.
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How to take lercanidipine
חזרה לתוכןBefore you start the treatment, read the manufacturer's printed information leaflet from inside the pack. It will give you more information about lercanidipine, and will also provide you with a full list of the side-effects which you could experience from taking it.
Lercanidipine is available in two strengths of tablet - 10 mg and 20 mg. The usual starting dose is 10 mg daily. If it becomes necessary, your doctor will increase your dose after a few weeks to 20 mg daily. Take the tablets exactly as your doctor tells you to.
It is likely that you will be advised to take your dose in the morning before breakfast. Try to take your doses at the same time each day. Having a routine will help you to remember to take your doses regularly.
Swallow the tablet with a drink of water. You should take lercanidipine when your stomach is empty, so about 30 minutes before a meal. This is because fatty food can increase the amount of lercanidipine your body absorbs, which could then lead to you experiencing side-effects.
If you forget to take a dose at your usual time, take it 30 minutes before your next meal. If you do not remember until the following day, leave out the missed dose. Do not take two doses together to make up for a forgotten dose.
להפיק את המרב מהטיפול שלך
חזרה לתוכןנסה לשמור על הפגישות הקבועות שלך עם הרופא. זה כדי שהרופא יוכל לבדוק את ההתקדמות שלך.
Do not drink grapefruit juice while you are on lercanidipine. This is because a substance in grapefruit juice increases the amount of lercanidipine in your bloodstream and this increases the risk of side-effects.
If you drink alcohol, ask your doctor for advice. Your doctor may recommend that you do not drink alcohol while you are on lercanidipine as the chance of side-effects (such as feeling dizzy and light-headed) is increased.
If you buy any medicines, check with a pharmacist that they are suitable for you to take alongside your prescribed medicines. This is because a number of medicines can interfere with lercanidipine and so may not be recommended for you.
If you are due to have an operation or any dental treatment, tell the person carrying out the treatment that you are taking lercanidipine tablets. Lercanidipine and some anaesthetics can interact, meaning that unwanted effects can be more likely.
Treatment with lercanidipine is usually long-term. Continue to take the tablets unless you are advised otherwise by your doctor. If it becomes necessary for you to stop treatment, your doctor may want you to reduce your dose gradually over a few days, as stopping taking lercanidipine suddenly can cause problems.
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Can lercanidipine cause problems?
חזרה לתוכןAlong with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. The table below contains some of the ones associated with lercanidipine. You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
Lercanidipine side-effects (these affect fewer than 1 in 100 people) | מה אני יכול לעשות אם אני חווה את זה? |
כאב ראש | This usually soon passes, but you can ask your pharmacist to recommend a suitable painkiller in the meantime |
תחושת סחרחורת | If this happens, do not drive and do not use tools or machines until you feel better |
Swollen ankles, feeling flushed, being aware of your heartbeat, a fast heartbeat | Speak with your doctor about these if any become troublesome or continue beyond a few days |
אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהטבליות, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.
How to store lercanidipine
חזרה לתוכןשמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.
יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.
מידע חשוב על כל התרופות
חזרה לתוכןמידע חשוב על כל התרופות
לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה מיד לחדר המיון בבית החולים המקומי שלך. קח איתך את המיכל, אפילו אם הוא ריק.
תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.
אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.
אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.
MHRA - דיווח על תגובות שליליות
דווח על תופעות לוואי חשודות לתרופות, חיסונים, סיגריות אלקטרוניות, תקריות עם מכשירים רפואיים, מוצרים פגומים או מזויפים לסוכנות הרגולטורית לתרופות ומוצרי בריאות כדי להבטיח שימוש בטוח ויעיל.

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שאלות נפוצות
What is high blood pressure and why is it important to treat?
High blood pressure, also known as hypertension, often does not make a person feel unwell. However, if it's not treated, it can cause damage to the heart and blood vessels. This can increase the risk of serious health problems like a heart attack or a stroke.
How exactly does lercanidipine help to lower blood pressure?
Lercanidipine is a calcium-channel blocker. It works by reducing the amount of calcium that enters certain muscle cells in your blood vessels. When these muscle cells receive less calcium, they relax, which causes your blood vessels to widen. This widening effect then leads to a reduction in your blood pressure.
Are there any specific foods or drinks I should avoid while taking lercanidipine?
Yes, you should avoid drinking grapefruit juice as it can increase the amount of lercanidipine absorbed into your bloodstream, potentially leading to more side-effects. Also, fatty foods can increase the absorption of lercanidipine, so it's best to take the tablet about 30 minutes before a meal when your stomach is empty.
What should I do if I forget to take a dose of lercanidipine?
If you forget a dose at your usual time, take it 30 minutes before your next meal. However, if you don't remember until the following day, you should skip the missed dose. Never take two doses together to make up for a forgotten dose.
How long will I need to take lercanidipine?
Treatment with lercanidipine is typically long-term. You should continue taking the tablets unless your doctor advises you otherwise. If your doctor decides you need to stop treatment, they may ask you to reduce your dose gradually over several days, as stopping suddenly can cause problems.
Can lercanidipine cause chest pain and what should I do?
While not listed as a common side effect of lercanidipine itself, the article states it is important to contact your doctor for advice straight away if you experience any chest pain after taking this medicine. This is a crucial safety instruction mentioned in the 'Important information about all medicines' section.
What kind of common side effects might I experience with lercanidipine?
Some common side effects, affecting fewer than 1 in 100 people, include headache, feeling dizzy, swollen ankles, feeling flushed, being aware of your heartbeat, and a fast heartbeat. These often improve over time as your body adjusts to the medication. If any side effects become troublesome or continue, you should speak with your doctor or pharmacist.
קריאה נוספת והפניות
- Manufacturer's PIL, Zanidip® 10 mg and 20 mg tablets; Recordati Pharmaceuticals Limited, The electronic Medicines Compendium. Dated April 2021.
- תרופות מלאות BNF מהדורה 89; האגודה הרפואית הבריטית והחברה המלכותית לפרמקולוגיה של בריטניה הגדולה, לונדון.
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About the authorView full bio

מייקל סטיוארט, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewer

סיד דג'אני
Sultan Dajani qualified at the London School of Pharmacy in 1994 and became the youngest elected member of the Royal Pharmaceutical Society council since its founding in 1842.
היסטוריית המאמר
המידע בעמוד זה נכתב ונבדק על ידי קלינאים מוסמכים.
Next review due: 8 May 2025
31 Mar 2025 | הגרסה האחרונה

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