Propranolol - a beta-blocker
Angilol, Bedranol, Beta-Prograne
נבדק על ידי Dr Colin Tidy, MRCGPעודכן לאחרונה על ידי Michael Stewart, MRPharmSLast updated 30 אוגוסט 2023
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Propranolol is a beta-blocker prescribed to treat a number of different conditions such as anxiety, high blood pressure, and angina.
If you are unsure why you are taking it, speak with your doctor.
The most common side effects of propranolol are feeling tired, cold hands and feet, disturbed sleep, and stomach upset.
At a glance
Propranolol is a beta-blocker medicine used for conditions like high blood pressure, angina, and anxiety symptoms.
It works by slowing down your heart's activity, reducing blood pressure and heart rate.
Common side effects include feeling tired, cold hands/feet, and disturbed sleep.
Do not stop taking propranolol suddenly, as this can cause problems.
Tell your doctor if you are pregnant, have asthma, diabetes, or other specific health conditions.
Alcohol can increase the blood pressure-lowering effects of propranolol.
Propranolol for anxiety symptoms can start working within an hour.
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About propranolol
סוג התרופה | A beta-adrenoceptor blocking medicine (often referred to as a beta-blocker) |
שימוש עבור | Hypertension; angina; arrhythmias; to protect the heart; anxiety symptoms; thyroid problems; to prevent migraines |
נקרא גם | Angilol®; Bedranol SR®; Beta-Prograne®; Half Beta-Prograne® |
זמין כ | Tablets, modified-release capsules and oral liquid medicine |
What is propranolol used for?
חזרה לתוכןPropranolol is a type of חוסמי בטא used to treat several medical conditions such as anxiety and high blood pressure. It works on the heart and blood vessels.
Propranolol helps ease the physical symptoms of חרדה, such as a fast heartbeat and trembling. Similar symptoms to these are also experienced by people with an פעילה יתר על המידה. Propranolol quickly relieves these types of symptoms.
It is also the beta-blocker which is commonly prescribed to help prevent migraines. Propranolol can be helpful for people who find other treatments for migraine unsuitable.
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How does propranolol work?
חזרה לתוכןPropranolol slows down the activity of your heart by stopping messages sent by some nerves to your heart. It does this by blocking tiny areas (called beta-adrenergic receptors) where the messages are received by your heart.
As a result, your heart beats more slowly and with less force. This allows the pressure of blood within your blood vessels to be reduced if you have לחץ דם גבוה (יתר לחץ דם), and helps to prevent abnormally fast heart rhythms (arrhythmias).
Because your heart is using less energy, this helps to reduce chest pain if you have אנגינה. Propranolol can also help to protect the heart following a התקף לב.
Side effects of propranolol
חזרה לתוכןThe most common side effects of propranolol are:
Feeling tired.
Cold hands and feet.
Feeling out of breath.
Disturbed sleep (insomnia).
Slow heartbeat.
You you also experience other common side effects such as:
Erectile dysfunction (impotence).
Reduce sexual desire (libido).
Mood changes.
כאב ראש.
Upset stomach.
You will find a full list in the manufacturer's information leaflet supplied with your medicine. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome.
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How to manage propranolol side effects
חזרה לתוכןCommon propranolol side effects (these affect fewer than 1 in 10 people) | מה אני יכול לעשות אם אני חווה את זה? |
מרגיש עייף | If this happens, do not drive and do not use tools or machines until you feel more awake |
Cold hands or feet, feeling breathless, disturbed sleep, a slow heartbeat | דבר עם הרופא שלך אם אחד מאלה הופך למטריד |
Less common side effects include impotence, reduced sexual desire, mood changes, headache, stomach upset | דבר עם הרופא שלך אם אחד מאלה הופך למטריד |
אם אתה חווה תסמינים נוספים שלדעתך עשויים להיות כתוצאה מהתרופה, פנה לרופא או לרוקח שלך לקבלת ייעוץ נוסף.
Who should not take propranolol?
חזרה לתוכןSome medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. For these reasons, before you start taking propranolol it is important that your doctor or pharmacist knows:
אם את בהריון, מנסה להיכנס להריון או מניקה.
אם יש לך בעיות בתפקוד הכבד שלך, או בתפקוד הכליות שלך.
If you have low blood pressure or poor circulation.
If you have asthma or any other breathing disorder.
אם יש לך רמות סוכר גבוהות בדם (סוכרת).
If you have a skin problem called psoriasis.
אם יש לך מצב הגורם לחולשת שרירים, הנקרא מיאסטניה גרביס.
If you have been told you have a slow heartbeat or heart block (a slow and irregular heartbeat).
If you have been told you have chest pain called Prinzmetal's angina (caused by spasms of your heart's blood vessels).
אם אתה נוטל תרופות אחרות כלשהן. זה כולל כל תרופה שאתה נוטל שניתן לרכוש ללא מרשם, כמו גם תרופות צמחיות ומשלימות.
If you have ever had an allergic reaction to a medicine, or if you have ever had any other serious allergic reaction.
How to take propranolol
חזרה לתוכןRead the manufacturer's printed information leaflet from inside the pack. It will give you more information about propranolol and will provide you with a full list of the side effects which you may experience from taking it.
Your doctor will tell you what dose of propranolol is right for you, and this information will be printed on the label of the pack to remind you.
Take propranolol exactly as your doctor tells you to. Propranolol tablets are usually prescribed to be taken in divided doses - so you may be prescribed two, three or four doses to take each day.
Propranolol capsules have a more prolonged action and are prescribed to be taken once daily. Swallow the capsule whole with a drink of water - do not chew or open the capsules.
Propranolol tablets and capsules are available in several different strengths. Each time you collect a fresh supply, it's a good idea to check the strength on the packet to make sure they are the strength you are expecting.
Try to take your doses at the same times of day each day, as this will help you to remember to take them regularly.
If you do forget to take a dose of propranolol, take it as soon as you remember unless your next dose is due. If your next dose is due then take the tablet/capsule which is due but leave out the forgotten one. Do not take two doses together to make up for missing one.
להפיק את המרב מהטיפול שלך
חזרה לתוכןנסה לשמור על הפגישות הקבועות שלך עם הרופא. זה כדי שהרופא יוכל לבדוק את ההתקדמות שלך.
Treatment with propranolol can often be long-term. Continue to take the tablets/capsules unless your doctor tells you to stop.
Stopping treatment suddenly can cause problems in some people, so your doctor may want you to reduce your dose gradually if this becomes necessary.
If you are due to have an operation or dental treatment, it is important to tell the person carrying out the treatment that you are taking a beta-blocker. This is because some anaesthetics may increase the risk of unwanted effects.
If you drink alcohol, ask your doctor for advice about taking propranolol and alcohol. Alcohol will add to the blood pressure-lowering effect of propranolol and so may not be recommended for you.
If you have diabetes, propranolol can block the symptoms of low blood sugar. Your doctor will advise you about this.
If you buy any medicines, check with a pharmacist that they are suitable for you to take. Some medicines (including some cough, cold and flu remedies) may not be.
Your doctor may give you dietary and lifestyle advice about eating a healthy diet, not smoking, and taking regular exercise. If so, it is important that you follow the advice you are given.
How to store propranolol
חזרה לתוכןשמור את כל התרופות מחוץ להישג ידם וראייתם של ילדים.
יש לאחסן במקום קריר ויבש, הרחק מחום ואור ישיר.
מידע חשוב על כל התרופות
חזרה לתוכןמידע חשוב על כל התרופות
לעולם אל תיקח יותר מהמינון שנקבע. אם אתה חושד שאתה או מישהו אחר אולי לקח מנת יתר של תרופה זו, פנה מיד לחדר המיון בבית החולים המקומי שלך. קח איתך את המיכל, אפילו אם הוא ריק.
תרופה זו מיועדת עבורך. לעולם אל תיתן אותה לאנשים אחרים, גם אם מצבם נראה דומה לשלך.
אל תשמרו תרופות שפג תוקפן או שאינן רצויות. קחו אותן לבית המרקחת המקומי שלכם שיטפל בהן עבורכם.
אם יש לך שאלות לגבי התרופה הזו, שאל את הרוקח שלך.
דווח על תופעות לוואי לתרופה או חיסון
אם אתה חווה תופעות לוואי, תוכל לדווח עליהן באינטרנט דרך ה Yellow Card website.
שאלות נפוצות
חזרה לתוכןCan I take sertraline and propranolol together?
Yes, sertraline and propranolol are sometimes prescribed together. Sertraline is an antidepressant, while propranolol is a beta-blocker often used for heart conditions or to reduce anxiety symptoms like palpitations
What should you avoid when taking propranolol?
When taking propranolol, you should be careful with other medicines that affect heart rate or blood pressure, such as certain heart medications, calcium channel blockers, or some asthma inhalers. Alcohol can also increase side effects like dizziness.
Is propranolol an antidepressant?
No, propranolol is not an antidepressant. It is a beta-blocker, mainly used to treat high blood pressure, heart conditions, and sometimes anxiety symptoms like palpitations or tremors. While it can help with certain physical effects of anxiety, it does not treat the mood aspects of depression.
How quickly does propranolol work for anxiety?
Propranolol can start working for anxiety-related physical symptoms, like a racing heart or tremors, within an hour. However, it does not treat the underlying mood aspects of anxiety. Its effects are usually short-term, so it’s often taken as needed before stressful situations.
How long does propranolol last?
Propranolol usually lasts 3–6 hours, or up to 24 hours for extended-release tablets, depending on dose and individual response.

לא בטוחים לגבי ערבוב תרופות?
בדוק אינטראקציות אפשריות בין תרופות, תוספים ומזונות לפני נטילתם יחד.
שאלות נפוצות
What is the difference between propranolol tablets and capsules?
Propranolol tablets are usually prescribed to be taken in divided doses, meaning you might take two, three, or four doses each day. Propranolol capsules have a more prolonged action and are typically prescribed to be taken only once daily. You should swallow the capsules whole with a drink of water and not chew or open them.
Are there any specific situations where I should be cautious when taking propranolol?
Yes, there are a few situations to be aware of. If you are going to have an operation or dental treatment, it's important to tell the person performing the treatment that you are taking a beta-blocker, as some anaesthetics can increase the risk of unwanted effects. If you drink alcohol, you should ask your doctor for advice because alcohol can add to the blood pressure-lowering effect of propranolol. If you have diabetes, propranolol can hide the symptoms of low blood sugar, so your doctor will need to advise you on this. Also, if you buy any other medicines, including some cough, cold, and flu remedies, check with a pharmacist to ensure they are suitable to take with propranolol.
What should I do if I forget a dose of propranolol?
If you forget to take a dose of propranolol, take it as soon as you remember, unless your next dose is due very soon. If your next dose is almost due, then you should just take that scheduled dose and skip the one you missed. It's important not to take two doses together to make up for a forgotten dose.
How long will I need to take propranolol?
Treatment with propranolol can often be long-term. You should continue to take the tablets or capsules for as long as your doctor tells you to. Do not stop treatment suddenly, as this can cause problems in some people. If your doctor decides that you should stop taking it, they may want you to gradually reduce your dose.
Can propranolol affect my blood sugar levels if I have diabetes?
Yes, if you have diabetes, propranolol can block the normal symptoms that indicate low blood sugar. Your doctor will provide specific advice on how to manage this while you are taking propranolol.
Where can I find a complete list of side effects for propranolol?
A full list of side effects for propranolol can be found in the manufacturer's information leaflet that comes supplied with your medicine. If you experience any other symptoms that you think might be due to the medicine, you should speak with your doctor or pharmacist for further advice.
קריאה נוספת והפניות
- Manufacturer's PIL, Propranolol Tablets 10 mg, 40 mg; Aurobindo Pharma - Milpharm Ltd, The electronic Medicines Compendium. Dated July 2022.
- Manufacturer's PIL, Beta-Prograne® 160 mg sustained release capsules; Tillomed Laboratories Ltd, The electronic Medicines Compendium. Dated February 2020.
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About the authorView full bio

מייקל סטיוארט, MRPharmS
Medicine Leaflet Review Manager – Contractor, Pharmacist
BPharm (Hons), MRPharmS
Michael is a community pharmacist practicing in the Midlands and South Yorkshire with more than 20 years’ experience advising on medicines and medical conditions. He has a strong background in healthcare training, having produced and delivered training courses for pharmacy teams and staff of residential care settings, including nurses. He has also contributed to pharmacy advisory boards for the management of low acuity conditions in the community.
About the reviewerView full bio

Dr Colin Tidy, MRCGP
General Practitioner, Medical Author
MBBS, MRCGP, MRCP (Paediatrics), DCH
Dr Colin Tidy is an NHS Doctor, based in Oxfordshire.
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